Susan's grandfather was deaf, and passed down a hereditary form of deafness within Susan's family as shown in Figure. A. Is this mutation most likely to be dominant or recessive? B. Is it carried on an autosome or a sex chromosome? Why? C. A complete SNP analysis has been done for all of the 11 grandchildren (4 affected, and 7 unaffected). In comparing these 11 SNP results, how long a haplotype block would you expect to find around the critical gene? How might you detect it? grandfather Susan

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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Assignments #5
Susan's grandfather was deaf, and passed down a hereditary form of deafness within Susan's family as shown in
Figure.
A. Is this mutation most likely to be dominant or recessive?
B. Is it carried on an autosome or a sex chromosome? Why?
C. A complete SNP analysis has been done for all of the 11 grandchildren (4 affected, and 7 unaffected). In
comparing these 11 SNP results, how long a haplotype block would you expect to find around the critical gene? How
might you detect it?
grandfather
Susan
Transcribed Image Text:Assignments #5 Susan's grandfather was deaf, and passed down a hereditary form of deafness within Susan's family as shown in Figure. A. Is this mutation most likely to be dominant or recessive? B. Is it carried on an autosome or a sex chromosome? Why? C. A complete SNP analysis has been done for all of the 11 grandchildren (4 affected, and 7 unaffected). In comparing these 11 SNP results, how long a haplotype block would you expect to find around the critical gene? How might you detect it? grandfather Susan
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