Suppose we want to estimate the concentration (µg/mL) of a specific dose of ampicillin in the urine after various periods of time. We recruit 25 volunteers who have received ampicillin and find they have a mean concentration of 7.0 µg/mL with a standard deviation of 2.0 µg/mL. Assume the underlying population distribution of concentrations is normally distributed.    How large a sample would be needed to ensure that the length of the CI in Problem above is 0.5 µg/mL assuming the sample standard deviation remains at 2.0 µg/mL?

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Suppose we want to estimate the concentration (µg/mL) of a specific dose of ampicillin in the urine after various periods of time. We recruit 25 volunteers who have received ampicillin and find they have a mean concentration of 7.0 µg/mL with a standard deviation of 2.0 µg/mL. Assume
the underlying population distribution of concentrations is normally distributed.

 

 How large a sample would be needed to ensure that the length of the CI in Problem above is 0.5 µg/mL assuming the sample standard deviation remains at 2.0 µg/mL?

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