Summarize what ketosis is metabolically
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
The body uses

Transcribed Image Text:Acetyl-CoA
H₂C
Acetone
CoA
B-Ketoacyl-CoA
thiolase
Acetoacetate
decarboxylase
HMG-CoA synthase
H₂C
H₂C
#focan
COA
H₂C
HMG-CoA lyase
co:4/
H₂C OH
S-CoA
на COA
Acetyl-CoA + H₂O
Acetyl-CoA
CH₂
-CoA
-CoA
Acetoacetyl-CoA
Acetyl-CoA
3-Hydroxy-3-methylglutaryl-CoA
OH
CH
(HMG-CoA)
Acetoacetate
NADH + H
NAD
CH ₂
D-B-Hydroxybutyrate
dehydrogenase
D-B-Hydroxybutyrate
Cholesterol
Export ketone
bodies to
the blood
Figure 16.15 The ketone bodies acetoacetate and D-B-
hydroxybutyrate are formed from two molecules of acetyl-CoA
in a three-step reaction pathway. Ketone bodies produced in the
liver are exported into the blood.
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