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Some microorganisms have evolved cellular machinery that carries out chemical transformations in a manner analogous to that of the pyruvate dehydrogenase complex (PDC). One example of these remarkable transformations is shown below. معلم H3C 1. TPP 2. lipoamide CH3 + 3. Coenzyme A H3C H H3C SCOA он Provide a complete curved-arrow mechanism for all three steps of this multistep enzymatic transformation. You may abbreviate the structure of Coenzyme A as "COA-SH" in your mechanism. You do not have to show a mechanism for the regeneration of the lipoamide cofactor.

Some microorganisms have evolved cellular machinery that carries out chemical transformations in a manner analogous to that of the pyruvate dehydrogenase complex (PDC). One example of these remarkable transformations is shown below. معلم H3C 1. TPP 2. lipoamide CH3 + 3. Coenzyme A H3C H H3C SCOA он Provide a complete curved-arrow mechanism for all three steps of this multistep enzymatic transformation. You may abbreviate the structure of Coenzyme A as "COA-SH" in your mechanism. You do not have to show a mechanism for the regeneration of the lipoamide cofactor.

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Some microorganisms have evolved cellular machinery that carries out chemical transformations in a manner analogous to that of the pyruvate dehydrogenase complex (PDC). One example of these remarkable transformations is shown below. معلم H3C 1. TPP 2. lipoamide CH3 + 3. Coenzyme A H3C H H3C SCOA он Provide a complete curved-arrow mechanism for all three steps of this multistep enzymatic transformation. You may abbreviate the structure of Coenzyme A as "COA-SH" in your mechanism. You do not have to show a mechanism for the regeneration of the lipoamide cofactor.
Transcribed Image Text:Some microorganisms have evolved cellular machinery that carries out chemical transformations in a manner analogous to that of the pyruvate dehydrogenase complex (PDC). One example of these remarkable transformations is shown below. معلم H3C 1. TPP 2. lipoamide CH3 + 3. Coenzyme A H3C H H3C SCOA он Provide a complete curved-arrow mechanism for all three steps of this multistep enzymatic transformation. You may abbreviate the structure of Coenzyme A as "COA-SH" in your mechanism. You do not have to show a mechanism for the regeneration of the lipoamide cofactor.
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