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Some antibiotics target peptidoglycan synthesis. What is a
molecular growth target of an antibiotic that inhibits
peptidoglycan synthesis?
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- why is peptidoglycan synthesis inportant in antibiotic activity? why do antibiotics not interfere with cell wall synthesis in the host cells?Most medically useful antibiotics interfere with either peptidoglycan synthesis or ribosome function. Why would the cytoplasmic membrane (in general) be a poor target for antibacterial medications?Most medically useful antibiotics interfere with either peptidogly¬can synthesis or ribosome function. Why would the cytoplasmic membrane be a poor target for antibacterial medications?
- The ribosome is the target for many important antibiotics. These drugs must discriminate between bacterial and eukaryotic ribosomes to achieve drug specificity and toxicity. For the two common antibiotics below, what is their mechanism of action and why are they more toxic to bacteria than eukaryotes? a) Tetracycline b) ErythromycinCan lactic acid culture infect the human gastrointestinal tract? If yes, why is this method not used to treat lactose-intolerant individuals?How is host cell lysis triggered after bacteriophage invasion? What are the outcomes to bacterial host physiology if the bacteriophage undergoes the lysogenic cycle?
- Most medically useful antibiotics interfere with either peptidoglycan synthesis or ribosome function. Why would the cell membrane be a poor target for antimicrobial medication?What bacterial structural target would make an antibacterial drug selective for gram-negative bacteria? Provide one example of an antimicrobial compound that targets this structure.Many antibiotics used in modern medicine are compounds made by fungi that inhibit bacterial protein synthesis. Describe the specific effect of the following antimicrobial drugs: (i) Tetracycline (ii) Puromycin (iii) Alpha-Amanitin
- With some level of toxic shock syndrome caused by the superantigen produced by Staphylococcus aureus, why the antibiotics are not effective after a certain point, even though the pathogen is susceptible to them?Why are protease inhibitors an effective treatment forhuman AIDS?In antibiotics, define the terms bacteriostatic and bacteriocidal. What are the mechanism of action and resistance of beta-lactam antibiotic. What are the mechanism of action for one antibiotic effective against methicillin-resistant S. aureus (MRSA).