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Snake population TTX Resistance 22 ± 6.6 No resistance Bear Lake, ID NFETFGNSIICLFEITTSAGWDGLL Warrenton, ORNFETFGNSIICL FETTSAGWDGLL 44±4.2 Benton, OR NFETFGNSII CLFETTSAAWDGLL 210 ± 60 Willow Creek, CA NFETFGN STICLFETTSAG WNVLL 12,000 Domain I Extracellular u cu cu Domain II Domain III Domain IV Extreme resistance

Snake population TTX Resistance 22 ± 6.6 No resistance Bear Lake, ID NFETFGNSIICLFEITTSAGWDGLL Warrenton, ORNFETFGNSIICL FETTSAGWDGLL 44±4.2 Benton, OR NFETFGNSII CLFETTSAAWDGLL 210 ± 60 Willow Creek, CA NFETFGN STICLFETTSAG WNVLL 12,000 Domain I Extracellular u cu cu Domain II Domain III Domain IV Extreme resistance

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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 what the image tells bout the TTX toxin of rough-skinned newts blocks the skeletal muscle sodium channel?

**Snake Population and TTX Resistance** **Overview:** This image presents a diagram of the skeletal muscle sodium channel, highlighting its structure and the tetrodotoxin (TTX) resistance among different snake populations. The diagram includes a table and a visual representation of the sodium channel. **Table of Snake Populations:** - **Bear Lake, ID:** Sequence - NFTFGNSICLFEITTSAGWDGLL **TTX Resistance:** 22 ± 6.6 (No resistance) - **Warrenton, OR:** Sequence - NFTFGNSICLFEVTSAGWDGLL **TTX Resistance:** 44 ± 4.2 - **Benton, OR:** Sequence - NFTFGNSICLFEVTSAGWDGLL **TTX Resistance:** 210 ± 60 - **Willow Creek, CA:** Sequence - NFTFGNSICLFEVTSAGWNVLL **TTX Resistance:** 12,000 (Extreme resistance) **Diagram of the Sodium Channel:** - The sodium channel is divided into four domains: Domain I, II, III, and IV. - Each domain is composed of segments across the cell membrane, with extracellular and intracellular orientations. - Variations in the amino acid sequences of these channels, indicated by different colored circles and letters (e.g., V, N, T), are associated with differing levels of resistance to TTX. - The increment in TTX resistance levels correlates with specific mutations at these sites. **Source:** Zimmer/Emlen, *Evolution: Making Sense of Life, 3e*, © 2020 W.H. Freeman and Company.
Transcribed Image Text:**Snake Population and TTX Resistance** **Overview:** This image presents a diagram of the skeletal muscle sodium channel, highlighting its structure and the tetrodotoxin (TTX) resistance among different snake populations. The diagram includes a table and a visual representation of the sodium channel. **Table of Snake Populations:** - **Bear Lake, ID:** Sequence - NFTFGNSICLFEITTSAGWDGLL **TTX Resistance:** 22 ± 6.6 (No resistance) - **Warrenton, OR:** Sequence - NFTFGNSICLFEVTSAGWDGLL **TTX Resistance:** 44 ± 4.2 - **Benton, OR:** Sequence - NFTFGNSICLFEVTSAGWDGLL **TTX Resistance:** 210 ± 60 - **Willow Creek, CA:** Sequence - NFTFGNSICLFEVTSAGWNVLL **TTX Resistance:** 12,000 (Extreme resistance) **Diagram of the Sodium Channel:** - The sodium channel is divided into four domains: Domain I, II, III, and IV. - Each domain is composed of segments across the cell membrane, with extracellular and intracellular orientations. - Variations in the amino acid sequences of these channels, indicated by different colored circles and letters (e.g., V, N, T), are associated with differing levels of resistance to TTX. - The increment in TTX resistance levels correlates with specific mutations at these sites. **Source:** Zimmer/Emlen, *Evolution: Making Sense of Life, 3e*, © 2020 W.H. Freeman and Company.
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