Shown in the table are partial sequences (coding strand) of the normal human hemoglobin and three variants that occur commonly in the human population. Some of these variants function as normal hemoglobin, however, some negatively affect hemoglobin function. Type of Hemoglobin Base Position 7 10 13 CTG ACC CCC 16.25 118 121 124 127 GAG AGC AAC AGA TTC GAG CTG ACC CCC GTG AGC AAC AGA TTC GAG Normal hemoglobin Allele Variant 1 Allele Variant 2 Allele Variant 3 CTG ACC CCC GAG AGC AAC AGA TCC GAG CTG ACC CCC GAG ACC AAC AGA TTC GAG (a) Which allele/s will MOST likely result in an anomalous phenotype? Answer: [Select] (b) Explain your answer in (a). Explanation: [Select] (c) Which allele/s will LEAST likely result in an anomalous phenotype? Answer: [Select] (d) One of the alleles code for a protein that tend to clump together. Which allele is it? (Hint: Recall what you learned from protein/amino acid structure.) Answer: [Select]

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
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Shown in the table are partial sequences (coding strand) of the normal human hemoglobin and three variants that occur commonly in the human
population. Some of these variants function as normal hemoglobin, however, some negatively affect hemoglobin function.
Type of Hemoglobin
Base Position
7 10 13
16.25 118 121 124 127
GAG AGC AAC AGA TTC GAG
CTG ACC CCC GTG AGC AAC AGA TTC GAG
Normal hemoglobin CTG ACC CCC
Allele Variant 1
Allele Variant 2
Allele Variant 3
CTG ACC CCC GAG AGC AAC AGA TCC GAG
CTG ACC CCC GAG ACC AAC AGA TTC GAG
(a) Which allele/s will MOST likely result in an anomalous phenotype?
Answer: [Select)
(b) Explain your answer in (a).
Explanation: [Select]
(c) Which allele/s will LEAST likely result in an anomalous phenotype?
Answer: [Select)
(d) One of the alleles code for a protein that tend to clump together. Which allele is it? (Hint: Recall what you learned from protein/amino acid
structure.)
Answer: [Select]
Transcribed Image Text:Shown in the table are partial sequences (coding strand) of the normal human hemoglobin and three variants that occur commonly in the human population. Some of these variants function as normal hemoglobin, however, some negatively affect hemoglobin function. Type of Hemoglobin Base Position 7 10 13 16.25 118 121 124 127 GAG AGC AAC AGA TTC GAG CTG ACC CCC GTG AGC AAC AGA TTC GAG Normal hemoglobin CTG ACC CCC Allele Variant 1 Allele Variant 2 Allele Variant 3 CTG ACC CCC GAG AGC AAC AGA TCC GAG CTG ACC CCC GAG ACC AAC AGA TTC GAG (a) Which allele/s will MOST likely result in an anomalous phenotype? Answer: [Select) (b) Explain your answer in (a). Explanation: [Select] (c) Which allele/s will LEAST likely result in an anomalous phenotype? Answer: [Select) (d) One of the alleles code for a protein that tend to clump together. Which allele is it? (Hint: Recall what you learned from protein/amino acid structure.) Answer: [Select]
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