Show how mutation and meiosis lead to genetic variation.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Show how mutation and meiosis lead to genetic variation.

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Step 1

Genetic variation is defined as the dissimilarity in the sequence of the DNA molecule in a population.  Variations in the gene pool can be observed at multiple levels and can be induced by factors like mutation, SINEs, LINEs, endogenous retroviruses, transposable elements, meiosis, and mutation.

Step 2

A mutation is defined as the change in the sequence (either due to substitution, deletion or addition of nucleotides) of a DNA molecule due to errors during DNA replication or other environmental factors like UV rays.  Any change due to mutation in the coding region of the DNA will be passed down the expression pathway through RNAs or proteins. RNAs and proteins act as the functional element and any change in their orientation or sequence (due to change in the DNA sequence) may render them non-functional or they may function abnormally.

Changes in the DNA sequence of germ cells will be passed down to the next generation and thus will be accumulated in the gene pool over generations leading to variation in the genetic makeup of the species.

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