Sexually Transmitted Disease Suppose a study examines the relative efficacy of penicil- lin and spectinomycin in treating gonorrhea. Three treat- ments are considered: (1) penicillin, (2) spectinomycin, low dose, and (3) spectinomycin, high dose. Three possible responses are recorded: (1) positive smear, (2) negative smear, positive culture, (3) negative smear, negative culture. The data in Table 10.25 are obtained. TABLE 10.25 Efficacy of different treatments for gonorrhea Treatment Penicillin Spectinomycin (low dose) Spectinomycin (high dose) Total + Smear 40 10 15 65 Response Smear + Culture 30 20 40 90 Smear - Culture 130 70 45 245 Total 200 100 100 400 10.25 Is there any relationship between the type of treatment and the response? What form does the relationship take?

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please only answer 10.25

**Sexually Transmitted Disease**

A study examines the relative efficacy of penicillin and spectinomycin in treating gonorrhea. Three treatments are evaluated: 
1. Penicillin
2. Spectinomycin, low dose
3. Spectinomycin, high dose

Three possible responses are recorded:
1. Positive smear
2. Negative smear, positive culture
3. Negative smear, negative culture

The data obtained are shown in Table 10.25.

---

**TABLE 10.25**  
*Efficacy of different treatments for gonorrhea*

| Treatment                | + Smear | – Smear + Culture | – Smear – Culture | Total |
|--------------------------|---------|-------------------|-------------------|-------|
| Penicillin               | 40      | 30                | 130               | 200   |
| Spectinomycin (low dose) | 10      | 20                | 70                | 100   |
| Spectinomycin (high dose)| 15      | 40                | 45                | 100   |
| **Total**                | **65**  | **90**            | **245**           | **400**|

**10.25** Is there any relationship between the type of treatment and the response? What form does the relationship take?

**10.26** Suppose that either a positive smear or a positive culture is regarded as a positive response and is distinguished from other outcomes.
Transcribed Image Text:**Sexually Transmitted Disease** A study examines the relative efficacy of penicillin and spectinomycin in treating gonorrhea. Three treatments are evaluated: 1. Penicillin 2. Spectinomycin, low dose 3. Spectinomycin, high dose Three possible responses are recorded: 1. Positive smear 2. Negative smear, positive culture 3. Negative smear, negative culture The data obtained are shown in Table 10.25. --- **TABLE 10.25** *Efficacy of different treatments for gonorrhea* | Treatment | + Smear | – Smear + Culture | – Smear – Culture | Total | |--------------------------|---------|-------------------|-------------------|-------| | Penicillin | 40 | 30 | 130 | 200 | | Spectinomycin (low dose) | 10 | 20 | 70 | 100 | | Spectinomycin (high dose)| 15 | 40 | 45 | 100 | | **Total** | **65** | **90** | **245** | **400**| **10.25** Is there any relationship between the type of treatment and the response? What form does the relationship take? **10.26** Suppose that either a positive smear or a positive culture is regarded as a positive response and is distinguished from other outcomes.
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