Sexually Transmitted Disease Suppose a clinical trial is conducted to test the efficacy of a new drug, spectinomycin, for treating gonorrhea in females. Forty-six patients are given a 4-g daily dose of the drug and are seen 1 week later, at which time 6 of the patients still have gonorrhea. *6.27 What is the best point estimate for p, the probability of a failure with the drug? *6.28 What is a 95% Cl for p? *6.29 Suppose we know penicillin G at a daily dose of 4.8 megaunits has a 10% failure rate. What can be said in com- paring the two drugs?

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Sexually Transmitted Disease
Suppose a clinical trial is conducted to test the efficacy of a new
drug, spectinomycin, for treating gonorrhea in females. Forty-six
patients are given a 4-g daily dose of the drug and are seen
1 week later, at which time 6 of the patients still have gonorrhea.
*6.27 What is the best point estimate for p, the probability
of a failure with the drug?
*6.28 What is a 95% CI for p?
*6.29 Suppose we know penicillin G at a daily dose of 4.8
megaunits has a 10% failure rate. What can be said in com-
paring the two drugs?
Transcribed Image Text:Sexually Transmitted Disease Suppose a clinical trial is conducted to test the efficacy of a new drug, spectinomycin, for treating gonorrhea in females. Forty-six patients are given a 4-g daily dose of the drug and are seen 1 week later, at which time 6 of the patients still have gonorrhea. *6.27 What is the best point estimate for p, the probability of a failure with the drug? *6.28 What is a 95% CI for p? *6.29 Suppose we know penicillin G at a daily dose of 4.8 megaunits has a 10% failure rate. What can be said in com- paring the two drugs?
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