Sexual differentiation begins close to 4 weeks after fertilization, but cannot be seen visually until about 6 weeks post fertilization. All fetuses begin with a ______________________ gonad that is able to become either ovaries or testes, depending on the presence or absence of the Y chromosome. If the Y chromosome is present, a region of the Y chromosome will begin expressing genes that start the process of masculinization of internal structures. This region is known as the ______________________________ region or ___________ for short. The expression of these genes causes the bipotential gonad to develop into the testes. Once the testes have started developing, two hormones, testosterone and Anti-MüllerianHormone are produced. Testosterone causes the _____________________ ducts to develop into the _____________________. Testosterone also causes the internal development of the __________________ and __________________. Anti-Müllerian Hormone causes the ______________________ ducts to degenerate. Testosterone will get converted into __________________________, a much more potent version of testosterone, which will allow for the development of the male external genitalia (penis and scrotum). If the Y chromosome is absent, the bipotential gonad will develop into the ovaries. The Wolffian ducts will degenerate and the Müllerian ducts will develop into the ___________________, _______________________ and part of the _________________. In the absence of DHT, the external genitalia will remain female and the labia, clitoris and vaginal opening
Sexual differentiation begins close to 4 weeks after fertilization, but cannot be seen visually until about 6 weeks post fertilization. All fetuses begin with a ______________________ gonad that is able to become either ovaries or testes, depending on the presence or absence of the Y chromosome.
If the Y chromosome is present, a region of the Y chromosome will begin expressing genes that start the process of masculinization of internal structures. This region is known as the ______________________________ region or ___________ for short. The expression of these genes causes the bipotential gonad to develop into the testes. Once the testes have started developing, two hormones, testosterone and Anti-MüllerianHormone are produced. Testosterone causes the _____________________ ducts to develop into the _____________________. Testosterone also causes the internal development of the __________________ and __________________. Anti-Müllerian Hormone causes the ______________________ ducts to degenerate. Testosterone will get converted into __________________________, a much more potent version of testosterone, which will allow for the development of the male external genitalia (penis and scrotum).
If the Y chromosome is absent, the bipotential gonad will develop into the ovaries. The Wolffian ducts will degenerate and the Müllerian ducts will develop into the ___________________, _______________________ and part of the _________________. In the absence of DHT, the external genitalia will remain female and the labia, clitoris and vaginal opening.
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