Sex-reversed females with XY were found to be missing SRY gene on their Y chromosomes, while sex-reversed males with XX were found to carry a portion of a Y chromosome that has the SRY gene. What can you conclude from these two cases? 1.Sex determination depends primarily on the combination of sex chromosomes and the presence of SRY gene.  2.X and Y chromosomes can’t pair up during meiosis because they are not true homologous chromosomes.  3.Nonreciprocal crossover could result in translocation of the SRY gene between X and Y chromosome. 4. The SRY gene has a key role to determine maleness.  5.The Y chromosome contains a gene that determine maleness.

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Sex-reversed females with XY were found to be missing SRY gene on their Y chromosomes, while sex-reversed males with XX were found to carry a portion of a Y chromosome that has the SRY gene. What can you conclude from these two cases?

1.Sex determination depends primarily on the combination of sex chromosomes and the presence of SRY gene.
 2.X and Y chromosomes can’t pair up during meiosis because they are not true homologous chromosomes.
 3.Nonreciprocal crossover could result in translocation of the SRY gene between X and Y chromosome.
4. The SRY gene has a key role to determine maleness.
 5.The Y chromosome contains a gene that determine maleness.
Expert Solution
Step 1: Introduction

Sex determination in humans is a complex process impacted by the combination of sex chromosomes and specific genes that play vital parts within the development of male or female characteristics. One such gene, the SRY (sex-determining region Y) gene, has been a subject of extensive research to understand its part in deciding maleness. This question digs into the centrality of the SRY gene based on observed cases of sex-reversed people and points to draw conclusions about its key part in sex assurance.

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