Scenario 1: MSA Brute-force Multiple Sequence Alignment, as you just saw, is O(L^n) , where L is the average sequence length and n is the number of sequences. Suppose you want to do an MSA on 50 sequences of average length 100. You choose 10 of your sequences and align them on your computer in 0.1 seconds. How long will it take to align your complete data set? Scenario 2: Sorting Suppose you blast a query against GenBank, and get 1,000,000 hits (it could happen!) all with different E-values. You want to sort the hits by E-value. You try sorting just 100 hits, and this takes 0.001 seconds. The algorithm is O(n * log(n)). How long will it take to sort your complete data set? For log, use base 10.

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