See the two reactions below that can be used to make alkylbenzenes.
Name one disadvantage for each reaction.
Friedel craft alkylation reaction allowed for th formation of alkyl benzenes from alkyl halides, but was plagued with unwanted supplemental activity that reduced its efficiency.
Disadvantage of Friedel craft alkylation reaction -
1) Carbocation Rearrangement - Only certain alkylbenzenes can be made due to the tendency of cations to rearrange.
2) Compound Limitations - Friedel-Crafts fails when used with compounds such as nitrobenzene and other strong deactivating systems.
3)Polyalkylation - Products of Friedel-Crafts are even more reactive than starting material. Alkyl groups produced in Friedel-Crafts Alkylation are electron-donating substituents meaning that the products are more susceptible to electrophilic attack than what we began with.
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