Ribosome ER signal xaquence Ass pokpeptidea being muda SRP bindtan ER signial sequence nd caum traralation to paun. SRP binda to an SAP receptor in the ER membrane, which a located nast toa channel. Forthis binding to oce, proteira within SRP wnd the SRP recaptor mut abo be bound by GTP. Cytomal ER membran ER lumen Charnel SRP receptor The GTPbinding proteina wthin SRP nd the SRP recaptor hydralyre their CTP, Caing the relemn of SRP. The lowa trunalation to reauma, and the polypeptide i threded through channal nto the ER lumen FIGURE 17.6 Tarwting of paypeptites lo the endoplamt retkulum mentrae via SRP. Ineukaryoes, ve ral categories of proicins are fiest largeled to the IR membrane via SRP. These include ecreied proleins z well as proleins that are destined to stay in the ER, Golgi apparatus, lysosomes, or vacuoles.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Why is GTP necessary for this process?

Ribosome
ER signal
xaquence
Ass pokpeptidea being muda
SRP bindtan ER signial sequence
nd caum traralation to paun.
SRP binda to an SAP receptor in the
ER membrane, which a located nast
toa channel. Forthis binding to oce,
proteira within SRP wnd the SRP
recaptor mut abo be bound by GTP.
Cytomal
ER membran
ER lumen
Charnel SRP receptor
The GTPbinding proteina wthin SRP
nd the SRP recaptor hydralyre their
CTP, Caing the relemn of SRP. The
lowa trunalation to reauma, and the
polypeptide i threded through
channal nto the ER lumen
FIGURE 17.6 Tarwting of paypeptites lo the endoplamt
retkulum mentrae via SRP. Ineukaryoes, ve ral categories of
proicins are fiest largeled to the IR membrane via SRP. These include
ecreied proleins z well as proleins that are destined to stay in the ER,
Golgi apparatus, lysosomes, or vacuoles.
Transcribed Image Text:Ribosome ER signal xaquence Ass pokpeptidea being muda SRP bindtan ER signial sequence nd caum traralation to paun. SRP binda to an SAP receptor in the ER membrane, which a located nast toa channel. Forthis binding to oce, proteira within SRP wnd the SRP recaptor mut abo be bound by GTP. Cytomal ER membran ER lumen Charnel SRP receptor The GTPbinding proteina wthin SRP nd the SRP recaptor hydralyre their CTP, Caing the relemn of SRP. The lowa trunalation to reauma, and the polypeptide i threded through channal nto the ER lumen FIGURE 17.6 Tarwting of paypeptites lo the endoplamt retkulum mentrae via SRP. Ineukaryoes, ve ral categories of proicins are fiest largeled to the IR membrane via SRP. These include ecreied proleins z well as proleins that are destined to stay in the ER, Golgi apparatus, lysosomes, or vacuoles.
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