Remember that hexose kinase is an enzyme required for hexose metabolism, a process that takes a S-carbon sugar and breaks it down into 2 pyruvate molecules. 5a. What specific metabolic process have we studied in which hexose metabolism occurs? 5b. How many steps does this pathway consist of? steps 5c. Overall, this metabolic process (hexose → 2 pyruvate) is exergonic. However, if you look at the individual reactions that makeup this process, they are a mix of endergonic and exergonic

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
Question

Please help with a b c and d

Remember that hexose kinase is an enzyme required for hexose metabolism, a process that takes a
6-carbon sugar and breaks it down into 2 pyruvate molecules.
5a. What specific metabolic process have we studied in which hexose metabolism occurs?
5b. How many steps does this pathway consist of?
steps
5c. Overall, this metabolic process (hexose → 2 pyruvate) is exergonic. However, if you look at the
individual reactions that makeup this process, they are a mix of endergonic and exergonic
reactions.
Is the preceding statement true or false?
If you selected true, describe the contribution of endergonic reactions to the overall exergonic
process. If false, explain why.
You discover that rather than being hormonally regulated (as seen above in humans), hexose kinase
is part of an operon in prokaryotic organisms. This operon is known as the "hexose operon" and it
regulates expression of the complete set of enzymes needed to convert a hexose sugar into 2
pyruvate molecules.
5d. Remembering that hexose metabolism is a highly conserved process among all branches of life,
how many genes do you expect to find in this operon? Explain your logic.
Like the lac operon, the hexose operon is controlled by a separate regulatory protein under the control
of its own promoter (see the schematic of the operon below). The hexose regulatory protein is
sensitive to fatty acyl CoA levels. When all hexose fuel sources are depleted, the bacteria switch to
lipid metabolism and fatty acyl CoA levels increase. This turns expression of the hexose operon off.
+1
+1
Regulatory Gene
Pregulator
Poperon
Hexose Operon Genes
regulator promoter
operon promoter
5e. The regulatory protein that controls expression of the hexose operons is a transcriptional
ACTIVTOR or REPRESSOR (circle one).
Transcribed Image Text:Remember that hexose kinase is an enzyme required for hexose metabolism, a process that takes a 6-carbon sugar and breaks it down into 2 pyruvate molecules. 5a. What specific metabolic process have we studied in which hexose metabolism occurs? 5b. How many steps does this pathway consist of? steps 5c. Overall, this metabolic process (hexose → 2 pyruvate) is exergonic. However, if you look at the individual reactions that makeup this process, they are a mix of endergonic and exergonic reactions. Is the preceding statement true or false? If you selected true, describe the contribution of endergonic reactions to the overall exergonic process. If false, explain why. You discover that rather than being hormonally regulated (as seen above in humans), hexose kinase is part of an operon in prokaryotic organisms. This operon is known as the "hexose operon" and it regulates expression of the complete set of enzymes needed to convert a hexose sugar into 2 pyruvate molecules. 5d. Remembering that hexose metabolism is a highly conserved process among all branches of life, how many genes do you expect to find in this operon? Explain your logic. Like the lac operon, the hexose operon is controlled by a separate regulatory protein under the control of its own promoter (see the schematic of the operon below). The hexose regulatory protein is sensitive to fatty acyl CoA levels. When all hexose fuel sources are depleted, the bacteria switch to lipid metabolism and fatty acyl CoA levels increase. This turns expression of the hexose operon off. +1 +1 Regulatory Gene Pregulator Poperon Hexose Operon Genes regulator promoter operon promoter 5e. The regulatory protein that controls expression of the hexose operons is a transcriptional ACTIVTOR or REPRESSOR (circle one).
Expert Solution
steps

Step by step

Solved in 2 steps with 2 images

Blurred answer
Knowledge Booster
Complications during life stages
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON