REGULATION OF GENE EXPRESSION Gene Regulatory transcription factors can activate or inhibit transcription. The arrangements and composition of nucleosomes influence transcription. DNA methylation (usually) inhibits transcription. Transcription pre-MRNA RNA processing Alternative splicing alters exon choices. RNA editing alters the base sequence of mRNAs. MRNA Small RNAS, called miRNAs and siRNAs, silence the translation of MRNA, a process called RNA interference. Translation Proteins that bind to the 5' end of MRNA regulate translation. MRNA stability may be influenced by RNA-binding proteins. Protein Posttranslatlonal modificatlons Feedback inhibition and covalent modifications regulate protein function. Functional protein fficient?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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At which of these levels is
regulation of gene expression most energy-efficient?

REGULATION OF
GENE EXPRESSION
Gene
Regulatory transcription factors
can activate or inhibit transcription.
The arrangements and composition
of nucleosomes influence transcription.
DNA methylation (usually) inhibits
transcription.
Transcription
pre-MRNA
RNA
processing
Alternative splicing alters exon
choices.
RNA editing alters the base
sequence of mRNAs.
MRNA
Small RNAS, called miRNAs and siRNAs, silence the
translation of MRNA, a process called RNA interference.
Translation
Proteins that bind to the 5' end of MRNA regulate translation.
MRNA stability may be influenced by RNA-binding proteins.
Protein
Posttranslatlonal
modificatlons
Feedback inhibition and covalent modifications
regulate protein function.
Functional protein
fficient?
Transcribed Image Text:REGULATION OF GENE EXPRESSION Gene Regulatory transcription factors can activate or inhibit transcription. The arrangements and composition of nucleosomes influence transcription. DNA methylation (usually) inhibits transcription. Transcription pre-MRNA RNA processing Alternative splicing alters exon choices. RNA editing alters the base sequence of mRNAs. MRNA Small RNAS, called miRNAs and siRNAs, silence the translation of MRNA, a process called RNA interference. Translation Proteins that bind to the 5' end of MRNA regulate translation. MRNA stability may be influenced by RNA-binding proteins. Protein Posttranslatlonal modificatlons Feedback inhibition and covalent modifications regulate protein function. Functional protein fficient?
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