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Regarding the production of therapeutic proteins, which one of the following statements is not correct? Glycosylation is a post-translational modification important for protein stability Human cell lines are increasingly popular to use for the production of human therapeutic proteins due to the likelihood of the product having appropriate post-translational modifications O Bioreactors designed for the growth of bacteria are not suitable for mammalian cells because such cals lack a cewa O Proteolysis at specific sites within a protein sequence can be essential to obtain a final product with the appropriate bioactivity When a protein becomes N-linked glycosylated, the glycan chain is most commonly added to aromatic amino acid residues

Regarding the production of therapeutic proteins, which one of the following statements is not correct? Glycosylation is a post-translational modification important for protein stability Human cell lines are increasingly popular to use for the production of human therapeutic proteins due to the likelihood of the product having appropriate post-translational modifications O Bioreactors designed for the growth of bacteria are not suitable for mammalian cells because such cals lack a cewa O Proteolysis at specific sites within a protein sequence can be essential to obtain a final product with the appropriate bioactivity When a protein becomes N-linked glycosylated, the glycan chain is most commonly added to aromatic amino acid residues

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Regarding the production of therapeutic proteins, which one of the following statements is not correct? Glycosylation is a post-translational modification important for protein stability Human cell lines are increasingly popular to use for the production of human therapeutic proteins due to the likelihood of the product having appropriate post-translational modifications Bioreactors designed for the growth of bacteria are not suitable for mammalian cells because such cells lack a cell wall O Proteolysis at specific sites within a protein sequence can be essential to obtain a final product with the appropriate bioactivity When a protein becomes N-linked glycosylated, the glycan chain is most commonly added to aromatic amino acid residues
Transcribed Image Text:Regarding the production of therapeutic proteins, which one of the following statements is not correct? Glycosylation is a post-translational modification important for protein stability Human cell lines are increasingly popular to use for the production of human therapeutic proteins due to the likelihood of the product having appropriate post-translational modifications Bioreactors designed for the growth of bacteria are not suitable for mammalian cells because such cells lack a cell wall O Proteolysis at specific sites within a protein sequence can be essential to obtain a final product with the appropriate bioactivity When a protein becomes N-linked glycosylated, the glycan chain is most commonly added to aromatic amino acid residues
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