Rank the set of substituents below in order of priority according to the Cahn-Ingold-Prelog sequence rules. 1 = highest priority. (a) —CO₂H (b) —CO,CH3 (c)-CH₂OH (d) -CH3
Reactive Intermediates
In chemistry, reactive intermediates are termed as short-lived, highly reactive atoms with high energy. They rapidly transform into stable particles during a chemical reaction. In specific cases, by means of matrix isolation and at low-temperature reactive intermediates can be isolated.
Hydride Shift
A hydride shift is a rearrangement of a hydrogen atom in a carbocation that occurs to make the molecule more stable. In organic chemistry, rearrangement of the carbocation is very easily seen. This rearrangement can be because of the movement of a carbocation to attain stability in the compound. Such structural reorganization movement is called a shift within molecules. After the shifting of carbocation over the different carbon then they form structural isomers of the previous existing molecule.
Vinylic Carbocation
A carbocation where the positive charge is on the alkene carbon is known as the vinyl carbocation or vinyl cation. The empirical formula for vinyl cation is C2H3+. In the vinyl carbocation, the positive charge is on the carbon atom with the double bond therefore it is sp hybridized. It is known to be a part of various reactions, for example, electrophilic addition of alkynes and solvolysis as well. It plays the role of a reactive intermediate in these reactions.
Cycloheptatrienyl Cation
It is an aromatic carbocation having a general formula, [C7 H7]+. It is also known as the aromatic tropylium ion. Its name is derived from the molecule tropine, which is a seven membered carbon atom ring. Cycloheptatriene or tropylidene was first synthesized from tropine.
Stability of Vinyl Carbocation
Carbocations are positively charged carbon atoms. It is also known as a carbonium ion.
![**Ranking Substituents by Priority**
According to the Cahn-Ingold-Prelog sequence rules, you are asked to rank the following substituents in order of priority. The highest priority is indicated by the number 1.
1. **Substituents:**
- (a) —CO₂H
- (b) —CO₂CH₃
- (c) —CH₂OH
- (d) —CH₃
**Instructions:**
Rank the substituents by selecting the appropriate number for each, using the dropdown options provided next to each substituent.
**Note:**
- Consider the atomic number and connectivity to determine the priority.
- The substituent with the highest atomic number receives the highest priority (1).
Use your understanding of the Cahn-Ingold-Prelog rules to complete the ranking.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fbe21ad11-6e18-4b63-a679-8109648f0f0b%2Feef0dbff-f6de-4a44-bd60-39f2da8cb27f%2Fl4mgkcrg_processed.png&w=3840&q=75)
![The image displays a part of a multiple-choice question interface related to chemistry.
At the top, there are two chemical structures labeled "(a)" and "(b)":
- (a) — CO₂H
- (b) — CO₂ (likely a continuation or part of a chemical formula)
Below these structures, there is a dropdown menu that seems to be used for selecting an answer. The menu currently shows a checkmark next to the number "1," indicating selection. Other options include the numbers "2," "3," and "4."
Underneath the dropdown, there are two buttons:
- A blue button labeled "Submit Answer"
- A gray button labeled "Try Another"
This interface likely allows users to select an answer choice and then submit it, or attempt the question again.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fbe21ad11-6e18-4b63-a679-8109648f0f0b%2Feef0dbff-f6de-4a44-bd60-39f2da8cb27f%2F48ko88n_processed.png&w=3840&q=75)
![](/static/compass_v2/shared-icons/check-mark.png)
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