QUESTION 4 In the reaction catalyzed by Triose phosphate isomerase, formation of the enediol intermedia involves transfer of substrate. from substrate onto the enzyme and from the enzyme back onto th O Oxygen Electrons O Hydrogen bonds Phosphate O Protons

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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QUESTION 4
In the reaction catalyzed by Triose phosphate isomerase, formation of the enediol intermediate
involves transfer of
from substrate onto the enzyme and from the enzyme back onto the
substrate.
O Oxygen
Electrons
Hydrogen bonds
Phosphate
O Protons
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Transcribed Image Text:QUESTION 4 In the reaction catalyzed by Triose phosphate isomerase, formation of the enediol intermediate involves transfer of from substrate onto the enzyme and from the enzyme back onto the substrate. O Oxygen Electrons Hydrogen bonds Phosphate O Protons Click Save and Submit to save and submit. Click Save All Answers to save all answers. Human Population..pdf Human Population.pdf 66 DII PriScn Home
Expert Solution
Step 1
  • The enzyme is dimeric with a molecular weight of approximately 54kD.
  • It mainly catalyzes the isomerization of a ketose dihydroxyacetone phosphate) to an aldose (glyceraldehyde phosphate) in glycolysis and gluconeogenesis pathway.
  • It is also involved in other metabolic biological processes which include fatty acid biosynthesis and the HMP shunt pathway.
  • Mutation of this enzyme results in an autosomal recessive disorder that leads to increased accumulation of dihydroxyacetone phosphate in the erythrocytes. 

 

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