QUESTION 4 Consider the depiction of a protein sequence below with ER signal sequences labeled as either start transfer sequences or stop transfer sequences... N terminus C terminus START transfer STOP transfer Assuming that the N-terminal signal sequence is removed after the protein is synthesized, 1) How many times will the finished protein traverse the membrane? 2) Will the N-terminus be located in the ER lumen or the cytoplasm? 3) Will the C-terminus be located in the ER lumen or the cytoplasm? 4) If this protein is brought to the membrane through vesicular transport, will the N-terminus be located inside of the cell or outside of the cell?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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QUESTION 4
Consider the depiction of a protein sequence below with ER signal sequences labeled as either start transfer sequences or stop transfer sequences.
N terminus
C terminus
START transfer
STOP transfer
Assuming that the N-terminal signal sequence is removed after the protein is synthesized,
1) How many times will the finished protein traverse the membrane?
2) Will the N-terminus be located in the ER lumen or the cytoplasm?
3) Will the C-terminus be located in the ER lumen or the cytoplasm?
4) If this protein is brought to the membrane through vesicular transport, will the N-terminus be located inside of the cell or outside of the cell?
Transcribed Image Text:QUESTION 4 Consider the depiction of a protein sequence below with ER signal sequences labeled as either start transfer sequences or stop transfer sequences. N terminus C terminus START transfer STOP transfer Assuming that the N-terminal signal sequence is removed after the protein is synthesized, 1) How many times will the finished protein traverse the membrane? 2) Will the N-terminus be located in the ER lumen or the cytoplasm? 3) Will the C-terminus be located in the ER lumen or the cytoplasm? 4) If this protein is brought to the membrane through vesicular transport, will the N-terminus be located inside of the cell or outside of the cell?
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