Question 3 3.1 Highlight the role of the Claisen and aldol reactions in the biosynthesis of natural products by outlining the biosynthesis of acetate-malonate derived orsellinic acid and phloracetophenone [11] OH CO₂H HO orsellinic acid OH O HO OH phloracetophe

Q: Carefully draw the keto form of the compound for which the enol is drawn; then draw it's "enolate"…

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Q: 27. (10) Write a reasonable mechanism OH -OH + for the following transformation. H₂SO4 -OCH₂CH₂CH3

A: Given acid  will protonate the substrate and make H2O into good leaving group.then water molecule…

Q: acetoacetate synthesis. More than one step may be required. Provide all reagents needed (2) Propose…

A: Here we have been asked to synthesize  3-butylhex-5-en-2-one from either diethyl malonate or ethyl…

Q: synthesize 3-methylhexanoic acid using an aldehyde and carbon dioxide as the only carbon sources and…

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Q: 7) Which of the following compounds cannot be prepared by an acetoacetic ester synthesis? Explain.…

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Q: Devise a synthesis of optically active (S)-fluoxetine (trade name Prozac) from the given starting…

A: Given,

Q: 2. Carefully draw the keto form of the compound for which the enol is drawn; then draw it's…

A: The first step of the reaction is the keto-enol tautomerism, which is formed by hydride (H-)…

Q: Devise a synthesis of optically active (S)-fluoxetine (trade name Prozac) from the given starting…

A: Given:

Q: Synthesize Ph-CH (OH)-CH3 starting with benzene & any other reagent of choice. 17.

A: First benzene treat with ethyl chloride and and AlCl3 then futher halogenation adds Cl at  benzylic…

Q: Q10 Using an aldol or crossed aldol condensation, suggest a synthesis of the following compounds: me…

A: In organic chemistry, an aldol condensation is a condensation reaction in which an enol or enolate…

Q: Synthesize the compund (Amlodipine) via Hantzsch dihydropyridine synthesis

A: The answer with mechanism is as follows:

Q: Aldol reactions are synthetically useful reactions that can be combined with other reactions to…

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Q: 23.2 Predict the enone product resulting from dehydration after aldol addition.

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Q: 49. Identify structures A and B in the following reaction sequence. 1).0₂ 2) DMS NaOH H₂O B C₁0H₁0…

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Q: Predict the major product formed when hexanoyl chloride is treated with excess LiAlH4, followed by…

A: Acid chlorides  react with LiAlH4 to give primary alcohols.

Q: A Draw a stepwise mechanism for the conversion of lactone A to ester B using HCI in ethanol. B is…

A: In the first step of the mechanism the carbonyl group undergoes protonation followed by attack of…

Q: Draw compounds B and C from the following reaction scheme. excess CH3I Ag20, H20 heat A B

A: In presence of excess of CH3I followed by oxidation by silver oxide, amines undergo Hoffmann…

Q: Identify the major product from the following series of reactions. NaOEt OEt EtO

A: NaOEt is a base that is used for abstract alpha hydrogen. Decarboxylation is a chemical reaction…

Q: HBr (excess)

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Q: A key step in the synthesis of donepezil (trade name Aricept) is a directed aldol reaction that…

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Q: 20. Provide the reactants and reaction conditions necessary for the following transformations.…

A: To provide structure of missing reactant

Q: 24. cont. NACN, (CH,),NCHO 30°C 1) NABH4 H 2) НC\ag) iBr KOH, CH;CH,OH f) 78°C Itt 1) Hg(O,CCF3)2,…

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