Just the answer QUESTION 28APC/C leads to the regulated proteolysis of M-cyclin through.binding and degrading it directly.the acetylation of CDK.the addition of a poly-methyl chain.Poly-ubiquitylation. QUESTION 31You are a new PhD student in the lab of Dr. Adenine and start noticing that many of the cells you are studying for your project have two centrosomes. Yourealize that a defect during one specific phase of the cell cycle could explain this double-centrosome phenotype. A defect during which phase is most likely tobe the culprit?G1 phase.Metaphase.G2 phase.O Interphase.

Answered: QUESTION 28 APC/C leads to the…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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QUESTION 31
You are a new PhD student in the lab of Dr. Adenine and start noticing that many of the cells you are studying for your project have two centrosomes. You
realize that a defect during one specific phase of the cell cycle could explain this double-centrosome phenotype. A defect during which phase is most likely to
be the culprit?
G1 phase.
Metaphase.
G2 phase.
O Interphase.

Expert Solution

Step 1

Cyclins undergo a series of cycle of synthesis and degradation in each cell cycle. The cyclin-CDK complex complex regulates the cell cycle. Cyclins undergo proteolysis at specific cell cycle stages, this destruction is necessary to inactivate Cyclin-CDK complex to regulate the cell cycle.

Cyclins undergo destruction by ubiquitylation to undergo proteolysis. This ubiquitylation is mediated by the E3 ubiquitin ligase. One such E3 ubiquitin ligase is APC/C.

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