Question 17 ( Here is a step from the citric acid cycle enzyme citrate synthase. His274 s-COA H- s-COA Asp375 Substrate is black and enzyme residues are green. What are the roles of His274 and Asp375 respectively? (Order is important.) Positioning substrate and transition state and an acid A base and a base An electrophile and a base An acid and a base OPositioning substrate and transition state and a base. An electrophile and an acid
Question 17 ( Here is a step from the citric acid cycle enzyme citrate synthase. His274 s-COA H- s-COA Asp375 Substrate is black and enzyme residues are green. What are the roles of His274 and Asp375 respectively? (Order is important.) Positioning substrate and transition state and an acid A base and a base An electrophile and a base An acid and a base OPositioning substrate and transition state and a base. An electrophile and an acid
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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![Question 17 (
Here is a step from the citric acid cycle enzyme citrate synthase.
His274
s-COA
H-
s-COA
Asp375
Substrate is black and enzyme residues are green. What are the roles of His274 and
Asp375 respectively? (Order is important.)
O Positioning substrate and transition state and an acid
A base and a base
O An electrophile and a base
An acid and a base
Positioning substrate and transition state and a base.
An electrophile and an acid](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F94e00d67-cb32-4e18-b283-48bfdb75761c%2F14318452-63a9-4573-9164-352248427df7%2F84nxbgd_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Question 17 (
Here is a step from the citric acid cycle enzyme citrate synthase.
His274
s-COA
H-
s-COA
Asp375
Substrate is black and enzyme residues are green. What are the roles of His274 and
Asp375 respectively? (Order is important.)
O Positioning substrate and transition state and an acid
A base and a base
O An electrophile and a base
An acid and a base
Positioning substrate and transition state and a base.
An electrophile and an acid
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