QUESTION 11 Which of the following factors contribute to the high phosphate group-transfer potential of ATP? (a) resonance stabilization of the hydrolyzed product of ATP (b) interaction of the terminal phosphoryl group with the ribose group in ADP (c) the interaction between the base amino group with the negative charges of the oxygen in ATP (d) the decrease in the electrostatic repulsion of charged oxygen upon the hydrolysis of ATP (e) both (a) and (d)
QUESTION 11 Which of the following factors contribute to the high phosphate group-transfer potential of ATP? (a) resonance stabilization of the hydrolyzed product of ATP (b) interaction of the terminal phosphoryl group with the ribose group in ADP (c) the interaction between the base amino group with the negative charges of the oxygen in ATP (d) the decrease in the electrostatic repulsion of charged oxygen upon the hydrolysis of ATP (e) both (a) and (d)
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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11
Transcribed Image Text:**Question 11**
Which of the following factors contribute to the high phosphate group-transfer potential of ATP?
- (a) *resonance stabilization* of the hydrolyzed product of ATP
- (b) interaction of the *terminal* phosphoryl group with the ribose group in ADP
- (c) the *interaction* between the base amino group with the negative charges of the oxygen in ATP
- (d) the *decrease* in the electrostatic repulsion of charged oxygen upon the hydrolysis of ATP
- (e) both (a) and (d)
**Question 12**
Which of the numbered arrows in the figure points toward a "high-energy" phosphoanhydride bond?
The diagram below depicts a molecular structure. There are five numbered arrows pointing at different parts of the molecule:
- Arrow 1 points to a nitrogen (N) atom connected to a base.
- Arrow 4 points to a phosphorus (P) atom connected by two single bonds and one double bond to oxygen (O) atoms, and to another section by a CH₂ group.
- Arrow 5 points to another phosphorus (P) atom in a similar linkage, highlighting the connection to other structural groups frequently involved in "high-energy" phosphate bonds.
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