QUESTION 11 A dipeptide has the composition TYR-ARG. Tyrosine is at the amino terminus and arginine is at the carboxyl terminus. Considering pKR of ARG = 12.5, pk1 of ARG = 2.17, pk2 of TYR = 9.11; determine the net charge on the dipeptide at pH 6.0. O +2 O +1
QUESTION 11 A dipeptide has the composition TYR-ARG. Tyrosine is at the amino terminus and arginine is at the carboxyl terminus. Considering pKR of ARG = 12.5, pk1 of ARG = 2.17, pk2 of TYR = 9.11; determine the net charge on the dipeptide at pH 6.0. O +2 O +1
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Question 11

Transcribed Image Text:QUESTION 11
A dipeptide has the composition TYR-ARG. Tyrosine is at the amino terminus and arginine is at the carboxyl terminus. Considering pKR of ARG = 12.5, pK, of ARG = 2.17, pk2 of TYR = 9.11; determine the net
charge on the dipeptide at pH 6.0:
O +2
0.1
QUESTION 12
Carefully analyze the structures of the peptides 1-4 and determine which of the peptide(s) will be least solunle in water?
Lys Glu-Ser-Arg-Asp
Peptide-2
Lys-Ser-Ala-Tyr-LysGlu-Lys-Arg-Arg-Asp
Peptide-3
Phe-Leu-Ser-Ala-Ile
Peptide-1
Peptide-4
O 2 and 3
O 2 and 4
O 1,2 and 4
O 1 and 2
O only 1
QUESTION 13
Titration of amino acids by a strong base, for example NaOH, results in two pks. The reaction occurring for the pk2 is correctly represented by which of the following reactions? Recall, Pka referes to titration of
- NH2 + OH -
–NH + H20
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