QUESTION 10 Carefully analyze the structures of the peptides 1-4 and determine which of the peptide(s) will carry a net zero charge at pH 7.0? (since question referst pH 7.0 yu should be oble to predict the charges on the side chain famino acids without needing the pka values) Phe-Leu-Ser-Ala-lle Lys-Glu-Ser-Arg-Asp| Lys-Ser-Ala-Tyr-Lys Gla-Lys-Arg-Arg-Asp Peptide- Peptide-3 Peptide-2 Peptide-4 O 2 and 4 01,2 and 4 O 2 and 3 O only 1 O 1 and 2
QUESTION 10 Carefully analyze the structures of the peptides 1-4 and determine which of the peptide(s) will carry a net zero charge at pH 7.0? (since question referst pH 7.0 yu should be oble to predict the charges on the side chain famino acids without needing the pka values) Phe-Leu-Ser-Ala-lle Lys-Glu-Ser-Arg-Asp| Lys-Ser-Ala-Tyr-Lys Gla-Lys-Arg-Arg-Asp Peptide- Peptide-3 Peptide-2 Peptide-4 O 2 and 4 01,2 and 4 O 2 and 3 O only 1 O 1 and 2
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
Question 10

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QUESTION 10
Carefully analyze the structures of the peptides 1- 4 and determine which of the peptide(s) will carry a net zero charge at pH 7.0? (since question referst pH 7.0 yu should be able to predict the charges on the side chain
famino acids without needing the pKa values)
Phe-Leu-Ser-Ala-leLy»-Glu-Ser-Arg-Asp Lys-Ser-Ala-Tyr-Lys Gla-Lys-Arg-Arg-Asp
Peptide-4
Peptide-3
Peptide-1
Peptide-2
O 2 and 4
O 1,2 and 4
O 2 and 3
O only 1
O 1 and 2
QUESTION 11
A dipeptide has the composition TYR-ARG. Tyrosine is at the amino terminus and arginine is at the carboxyl terminus. Considering pKR of ARG = 12.5, pk1 of ARG = 2.17, pk2 of TYR = 9.11; determine the net
charge on the dipeptide at pH 6.0
O +2
0.1
QUESTION 12
Carefully analyze the structures of the peptides 1- 4 and determine which of the peptide(s) will be least solunle in water?
Ser-Arg-Asp Lys-Ser-Ala-Tyr-Lys Glu-Lys-Arg-Arg-Asp
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