## Question 1With bacterial meningitis, we're going to see that the pathogens typically colonize part of the airway before ending up in the CSF via "hematogenous spread". Given that a root in the word hematogenous is "hema" how do these pathogens get from the airway to the CSF?- O via the blood- O they are carried there by macrophages- O they burrow directly from the back of the throat to the arachnoid mater.---## Question 2We know that the LPS in the cell wall of Gram negative bacteria promotes inflammation. Inflammation is responsible for some of the signs and symptoms of meningitis. Given all this, can pathogens OTHER THAN Gram negative bacteria cause meningitis?- O Yes, viruses and fungi are Gram positive pathogens that can cause meningitis.- O No, LPS must be present for inflammation to occur.- O Yes, for example the pneumococcus---Click Save and Submit to save and submit. Click Save All Answers to save all answers.

QUESTION 1 With bacterial meningitis, we're going to see that the pathogens typically colonize part of the airway before ending up in the CSF via "hematogenous spread" Given that a root in the word hematogenous is "hema" how do these pathogens get from the airway to the CSF? Ans- via the blood Explanation- There are various routes via which infection spreads in pur body. It can be:-Hematogenous spread,lymphatic spread ,local invasion. The Hematogenous spread means the spread pf infection via blood to other parts of the body. The bacteria or toxin or any pathogen gets disseminated in blood and spread to various parts. In biology word 'Hema' is related with blood , like for example hematopoiesis (means synthesis of blood and its constituent), hemangioma ( blood vessel tumor). QUESTION 2 We know that the LPS in the cell wall of Gram negative bacteria promotes inflammation. Inflammation is responsible for some of the signs and symptoms of meningitis. Given all this, can pathogens OTHER THAN Gram negative bacteria cause meningitis? Ans- Yes, for example the pneumococcus Explanation- pneumococcus is a gram positive bacteria and it also causes meningitis. For inflammation its not that only LPS can cause it. It can be caused by any antigen which is foreign to our immune cells. First option is incorrect because viruses are not gram positive since they can't be visualised by gram staining. And yes viruses also cause meningitis.