Question 1: (6 marks) The following diagram shows the parental DNA for two replication forks that are approaching one another from the left and right. (Note: Each linear line represents a single strand of DNA.) (a) Annotate the diagram (inside each fork) so that it accurately shows the result of nucleotide polymerization through the action of the replisome, prior to any activity by DNA Pol I and DNA ligase. Be sure to label the polarity of all generated nucleic acids. Indicate by colour (eg powerpoint line colour) which sections represent DNA or RNA. For the leading strand, you can assume that replication processes started at the ends furthest away from the fork (4 marks) (b) Add a drawing of DnaB enzyme to the diagram to show where it would bind and its direction of movement if ATP were added to this protein-DNA complex. (2 marks) 5' 3" Fork 1 3' Fork 2 5'
Question 1: (6 marks) The following diagram shows the parental DNA for two replication forks that are approaching one another from the left and right. (Note: Each linear line represents a single strand of DNA.) (a) Annotate the diagram (inside each fork) so that it accurately shows the result of nucleotide polymerization through the action of the replisome, prior to any activity by DNA Pol I and DNA ligase. Be sure to label the polarity of all generated nucleic acids. Indicate by colour (eg powerpoint line colour) which sections represent DNA or RNA. For the leading strand, you can assume that replication processes started at the ends furthest away from the fork (4 marks) (b) Add a drawing of DnaB enzyme to the diagram to show where it would bind and its direction of movement if ATP were added to this protein-DNA complex. (2 marks) 5' 3" Fork 1 3' Fork 2 5'
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Question 1: (6 marks)
The following diagram shows the parental DNA for two replication forks that are approaching one another from the left and right.
(Note: Each linear line represents a single strand of DNA.)
(a) Annotate the diagram (inside each fork) so that it accurately shows the result of nucleotide polymerization through the action
of the replisome, prior to any activity by DNA Pol I and DNA ligase. Be sure to label the polarity of all generated nucleic acids.
Indicate by colour (eg powerpoint line colour) which sections represent DNA or RNA. For the leading strand, you can assume that
replication processes started at the ends furthest away from the fork (4 marks)
(b) Add a drawing of DnaB enzyme to the diagram to show where it would bind and its direction of movement if ATP were added to
this protein-DNA complex. (2 marks)
5'
3"
Fork 1
3'
Fork 2
5'
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