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Q8. (1) Complete the following genetic diagram to show how parents who did not suffer from haemophilia, could have a son wit h haemophilia but also other children who did not suffer from haemophilia. Genotype of parents Genotype of gametes Phenotype of parents Normal male Normal female Genotype of offspring Phenotype of offspring (1) What is the probability of the couple having a daughter with haemophilia? What is the probability of the couple having another son with haemophilia?

Q8. (1) Complete the following genetic diagram to show how parents who did not suffer from haemophilia, could have a son wit h haemophilia but also other children who did not suffer from haemophilia. Genotype of parents Genotype of gametes Phenotype of parents Normal male Normal female Genotype of offspring Phenotype of offspring (1) What is the probability of the couple having a daughter with haemophilia? What is the probability of the couple having another son with haemophilia?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Assessment criteria 3.1.3.2, 3.3 Q7. Haemophiliacs possess a non-functional form of the gene responsible for the production of blood clotting factors. Shown below is the occurrence of haemophilia in one family. = male O = female = male haemophiliac 2 sing the following symbols: 8 HE dominant allele h = recessive allele All poram/male, genotype is_HH All affected male, genotype is bb. All noramshowing female genotype is_HH/Hh 1) State the genotypes of the following individuals. Individual Genotype Hh₂ 2 HH 3 HH/Hb 5 b.b 6 HH 9 Hh. 2) On the basis of the information provided, is the inheritance of haemophilia: (i) autosomal or sex-linked? Sex-linked (ii) dominant or recessive? Recessive 3) State the probability of individual 8 being a carrier of haemophilia. Completed forms to be made available for external moderation. Individual 8 is a female and is a daughter of individual 1 and 2. Individual 1 x individual 2 XHXhXXHY XH XH XHXH normal female XHY Y normal male Thus the probability that individual 8 is a carrier is 50%. 12 10 Xh XHXh normal but carrier female XhX Haemophilic male
Transcribed Image Text:Assessment criteria 3.1.3.2, 3.3 Q7. Haemophiliacs possess a non-functional form of the gene responsible for the production of blood clotting factors. Shown below is the occurrence of haemophilia in one family. = male O = female = male haemophiliac 2 sing the following symbols: 8 HE dominant allele h = recessive allele All poram/male, genotype is_HH All affected male, genotype is bb. All noramshowing female genotype is_HH/Hh 1) State the genotypes of the following individuals. Individual Genotype Hh₂ 2 HH 3 HH/Hb 5 b.b 6 HH 9 Hh. 2) On the basis of the information provided, is the inheritance of haemophilia: (i) autosomal or sex-linked? Sex-linked (ii) dominant or recessive? Recessive 3) State the probability of individual 8 being a carrier of haemophilia. Completed forms to be made available for external moderation. Individual 8 is a female and is a daughter of individual 1 and 2. Individual 1 x individual 2 XHXhXXHY XH XH XHXH normal female XHY Y normal male Thus the probability that individual 8 is a carrier is 50%. 12 10 Xh XHXh normal but carrier female XhX Haemophilic male
Individual 8 is a female and is a daughter of individual 1 and 2. individual 1 x individual 2 XXXXHY XH XH XHXh normal but carrier female XHXH normal female XHY Y normal male Haemophilic male Thus the probability that individual 8 is a carrier is 50%. 4) Explain Explain hy hy only females can be carriers of haemophilia. Haemophilia is a sex linked recessive disease suggesting that only females can be carrier and not males because females carry two X chromosomes and males carry only one X chromosome. The mutation in this disease occurs in the X chromosome. As the recessive character is only expressed when both the Alleles in a gene are mutated so females usually do not suffer with the disease but they can be carriers that is in them one allele is normal which is dominant and one allele is recessive which is abnormal but in males there is only one X chromosome and if it is mutated then he would be suffering from the disease and if it is not then he would be normal. So no carriers for male. Q8. (1) Complete the following genetic diagram to show how parents who did not suffer from haemophilia, could have a son wit h haemophilia but also other children who did not suffer from haemophilia. Phenotype of parents Genotype of parents Genotype of gametes Normal male Normal female Genotype of offspring Phenotype of offspring (0) What is the probability of the couple having a daughter with haemophilia? What is the probability of the couple having another son with haemophilia? (ii) Q9. Who's gonna take you home tonight? There has been a mix up in the maternity ward. The babies have managed to remove their wrist
Transcribed Image Text:Individual 8 is a female and is a daughter of individual 1 and 2. individual 1 x individual 2 XXXXHY XH XH XHXh normal but carrier female XHXH normal female XHY Y normal male Haemophilic male Thus the probability that individual 8 is a carrier is 50%. 4) Explain Explain hy hy only females can be carriers of haemophilia. Haemophilia is a sex linked recessive disease suggesting that only females can be carrier and not males because females carry two X chromosomes and males carry only one X chromosome. The mutation in this disease occurs in the X chromosome. As the recessive character is only expressed when both the Alleles in a gene are mutated so females usually do not suffer with the disease but they can be carriers that is in them one allele is normal which is dominant and one allele is recessive which is abnormal but in males there is only one X chromosome and if it is mutated then he would be suffering from the disease and if it is not then he would be normal. So no carriers for male. Q8. (1) Complete the following genetic diagram to show how parents who did not suffer from haemophilia, could have a son wit h haemophilia but also other children who did not suffer from haemophilia. Phenotype of parents Genotype of parents Genotype of gametes Normal male Normal female Genotype of offspring Phenotype of offspring (0) What is the probability of the couple having a daughter with haemophilia? What is the probability of the couple having another son with haemophilia? (ii) Q9. Who's gonna take you home tonight? There has been a mix up in the maternity ward. The babies have managed to remove their wrist
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