Put the following steps of the Ras/MAP pathway in the correct order. MAPK dimerize and phosphorylates downstream transcription factors activating them. Ras-GTP undergoes hydrolysis forming Ras-GDP and Ras dissociates from MAPKKK MAPKKK phosphorylates MAPKK activating it, which in turn phosphorylates MAPK. Active Ras binds inactive MAPKKK causing a conformational change in MAPKKK that results in it's activation.
Put the following steps of the Ras/MAP pathway in the correct order. MAPK dimerize and phosphorylates downstream transcription factors activating them. Ras-GTP undergoes hydrolysis forming Ras-GDP and Ras dissociates from MAPKKK MAPKKK phosphorylates MAPKK activating it, which in turn phosphorylates MAPK. Active Ras binds inactive MAPKKK causing a conformational change in MAPKKK that results in it's activation.
Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter23: Enzymes
Section: Chapter Questions
Problem 23.12P
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Put the following steps of the Ras/MAP pathway in the correct order.
MAPK dimerize and phosphorylates downstream transcription factors activating them.
Ras-GTP undergoes hydrolysis forming Ras-GDP and Ras dissociates from
MAPKKK
MAPKKK phosphorylates MAPKK activating it, which in turn phosphorylates MAPK.
Active Ras binds inactive MAPKKK causing a conformational change in MAPKKK that results in it's activation.
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