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Prostate cells usually require testosterone and other androgens to survive. But some prostate cancer cells thrive despite treatments that eliminate androgens. One hypothesis is that estrogen, often considered a female hormone, may be activating genes normally controlled by an androgen in these cancer cells. Part A Choose the experiments to test this hypothesis. Select all that apply. O Look for evidence of transcription or translation of the genes of interest in the absence of androgens. O Look for the presence of an estrogen-receptor complex in the nuclei of prostate cancer cells. O Use a treatment to eliminate estrogen, and note the effect on the proliferation of prostate cancer cells. O Look for evidence of transcription or translation of the genes of interest in the presence of androgens. O Look for the presence of an estrogen-receptor complex in the nuclei of normal prostate cells. O Look for the presence of G protein-coupled receptors in prostate cancer cells.

Prostate cells usually require testosterone and other androgens to survive. But some prostate cancer cells thrive despite treatments that eliminate androgens. One hypothesis is that estrogen, often considered a female hormone, may be activating genes normally controlled by an androgen in these cancer cells. Part A Choose the experiments to test this hypothesis. Select all that apply. O Look for evidence of transcription or translation of the genes of interest in the absence of androgens. O Look for the presence of an estrogen-receptor complex in the nuclei of prostate cancer cells. O Use a treatment to eliminate estrogen, and note the effect on the proliferation of prostate cancer cells. O Look for evidence of transcription or translation of the genes of interest in the presence of androgens. O Look for the presence of an estrogen-receptor complex in the nuclei of normal prostate cells. O Look for the presence of G protein-coupled receptors in prostate cancer cells.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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SCIENTIFIC INQUIRY Prostate cells usually require testosterone and other androgens to survive. But some prostate cancer cells thrive despite treatments that eliminate androgens. One hypothesis is that estrogen, often considered a female hormone, may be activating genes normally controlled by an androgen in these cancer cells. Part A Choose the experiments to test this hypothesis. Select all that apply. Look for evidence of transcription or translation of the genes of interest in the absence of androgens. Look for the presence of an estrogen-receptor complex in the nuclei of prostate cancer cells. Use a treatment to eliminate estrogen, and note the effect on the proliferation of prostate cancer cells. Look for evidence of transcription or translation of the genes of interest in the presence of androgens. Look for the presence of an estrogen-receptor complex in the nuclei of normal prostate cells. Look for the presence of G protein-coupled receptors in prostate cancer cells.
Transcribed Image Text:SCIENTIFIC INQUIRY Prostate cells usually require testosterone and other androgens to survive. But some prostate cancer cells thrive despite treatments that eliminate androgens. One hypothesis is that estrogen, often considered a female hormone, may be activating genes normally controlled by an androgen in these cancer cells. Part A Choose the experiments to test this hypothesis. Select all that apply. Look for evidence of transcription or translation of the genes of interest in the absence of androgens. Look for the presence of an estrogen-receptor complex in the nuclei of prostate cancer cells. Use a treatment to eliminate estrogen, and note the effect on the proliferation of prostate cancer cells. Look for evidence of transcription or translation of the genes of interest in the presence of androgens. Look for the presence of an estrogen-receptor complex in the nuclei of normal prostate cells. Look for the presence of G protein-coupled receptors in prostate cancer cells.
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