Propose an efficient synthesis for the given transformation. O-0 This transformation can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A t-BUOK 1) HC=CNa; 2) H₂O* K MeONa B 1); 2) H₂O* G NaH DMP or PCC 1):2) H₂0 H MCPBA (RCO₂H) M MeOH, H₂SO4 D Mg 1 Br₂, hv N H₂SO4, H₂O, HgSO4 E H₂, Lindlar's cat. J HBr (xs), heat 1) R₂BH; 2) H₂O₂ NaOH

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
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Chapter18: Functional Derivatives Of Carboxylic Acids
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Propose an efficient synthesis for the given transformation.
o-a
This transformation can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in
the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution,
provide just one answer.
A
t-BuOK
F
1) HC#CNa; 2)
H3O+
K
MeONa
B
1):2)
H₂O*
G
NaH
L
DMP or PCC
с
1):2) H30+
H
MCPBA
(RCO 3H)
M
MeOH, H₂SO4
D
Mg
1
Br₂, hv
N
H₂SO4, H₂O,
HgSO4
E
H₂, Lindlar's cat.
J
HBr (xs), heat
1) R₂BH; 2) H₂O₂,
NaOH
Transcribed Image Text:Propose an efficient synthesis for the given transformation. o-a This transformation can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A t-BuOK F 1) HC#CNa; 2) H3O+ K MeONa B 1):2) H₂O* G NaH L DMP or PCC с 1):2) H30+ H MCPBA (RCO 3H) M MeOH, H₂SO4 D Mg 1 Br₂, hv N H₂SO4, H₂O, HgSO4 E H₂, Lindlar's cat. J HBr (xs), heat 1) R₂BH; 2) H₂O₂, NaOH
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