Propose an efficient synthesis for the following transformation: Br The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagents in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A. conc. H₂SO4, heat B. D. H₂, Lindlar's cat. 1) H 2) H3O* workup E. HC=CNa c. ¹) 2) H3O+ workup F. Mg, ether

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**Efficient Synthesis for the Given Transformation**

**Objective:**
Propose an efficient synthesis for the transformation of a bromobenzene derivative to an alkene.

**Transformation Overview:**
The molecular structure shown involves a bromine atom on a benzene ring transforming into a substitution that results in the formation of an alkene side chain with one carbon-carbon double bond.

**Instructions:**
The transformation can be achieved using the appropriate sequence of reagents from the list below. Please select the necessary reagents in the correct order and represent them as a continuous string of letters (e.g., "EBF"). If multiple solutions exist, provide only one answer.

**Reagents List:**

- **A.** Concentrated H₂SO₄, heat
- **B.** 
  1) Formaldehyde
  2) H₃O⁺ workup
- **C.** 
  1) Epoxide
  2) H₃O⁺ workup
- **D.** H₂, Lindlar’s catalyst
- **E.** HC≡CNa (Sodium acetylide)
- **F.** Mg, ether

**Approach:**
Identify the correct sequence and combination of reagents from the list to efficiently achieve the desired alkene synthesis from the given halogenated starting material.
Transcribed Image Text:**Efficient Synthesis for the Given Transformation** **Objective:** Propose an efficient synthesis for the transformation of a bromobenzene derivative to an alkene. **Transformation Overview:** The molecular structure shown involves a bromine atom on a benzene ring transforming into a substitution that results in the formation of an alkene side chain with one carbon-carbon double bond. **Instructions:** The transformation can be achieved using the appropriate sequence of reagents from the list below. Please select the necessary reagents in the correct order and represent them as a continuous string of letters (e.g., "EBF"). If multiple solutions exist, provide only one answer. **Reagents List:** - **A.** Concentrated H₂SO₄, heat - **B.** 1) Formaldehyde 2) H₃O⁺ workup - **C.** 1) Epoxide 2) H₃O⁺ workup - **D.** H₂, Lindlar’s catalyst - **E.** HC≡CNa (Sodium acetylide) - **F.** Mg, ether **Approach:** Identify the correct sequence and combination of reagents from the list to efficiently achieve the desired alkene synthesis from the given halogenated starting material.
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