Propose a reasonable synthetic route for the preparation of the substituted benzene derivative shown below. You may use whatever reagents are necessary to transform the starting molecule into the desired product. [NOTE: this problem can also be answered correctly in three steps too. If you choose that route, then put steps 2 and 3 in the step 2 answer box.] CH=CH2 step 1 step 2 Step 1 reagent/reagents = Step 2 reagent/reagents = %3D
Reactive Intermediates
In chemistry, reactive intermediates are termed as short-lived, highly reactive atoms with high energy. They rapidly transform into stable particles during a chemical reaction. In specific cases, by means of matrix isolation and at low-temperature reactive intermediates can be isolated.
Hydride Shift
A hydride shift is a rearrangement of a hydrogen atom in a carbocation that occurs to make the molecule more stable. In organic chemistry, rearrangement of the carbocation is very easily seen. This rearrangement can be because of the movement of a carbocation to attain stability in the compound. Such structural reorganization movement is called a shift within molecules. After the shifting of carbocation over the different carbon then they form structural isomers of the previous existing molecule.
Vinylic Carbocation
A carbocation where the positive charge is on the alkene carbon is known as the vinyl carbocation or vinyl cation. The empirical formula for vinyl cation is C2H3+. In the vinyl carbocation, the positive charge is on the carbon atom with the double bond therefore it is sp hybridized. It is known to be a part of various reactions, for example, electrophilic addition of alkynes and solvolysis as well. It plays the role of a reactive intermediate in these reactions.
Cycloheptatrienyl Cation
It is an aromatic carbocation having a general formula, [C7 H7]+. It is also known as the aromatic tropylium ion. Its name is derived from the molecule tropine, which is a seven membered carbon atom ring. Cycloheptatriene or tropylidene was first synthesized from tropine.
Stability of Vinyl Carbocation
Carbocations are positively charged carbon atoms. It is also known as a carbonium ion.
![Propose a reasonable synthetic route for the preparation of the substituted benzene
derivative shown below. You may use whatever reagents are necessary to transform
the starting molecule into the desired product.
[NOTE: this problem can also be answered correctly in three steps too. If you choose
that route, then put steps 2 and 3 in the step 2 answer box.]
CH=CH2
step 1
step 2
Step 1 reagent/reagents =
Step 2 reagent/reagents =](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fa6c5565a-787b-43d3-b23e-780453faf6da%2F1c75f407-a8ad-4369-80b0-1227713f8b7e%2F85yzwy6_processed.png&w=3840&q=75)
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