Problem 5. Paclitaxel, marketed as Taxol, is a chemotherapeutic drug used to treat a number of cancers. Carefully examine the structure of Taxol indicated below and identify six unique functional groups. Circle the functional group and write its name alongside. A list of functional groups you are required to know is provided below; some of these functional groups may not be present in Taxol. (Textbook section 2.3) CHEM 3361L OH NH O O" OH ОН О Indicate the total number of following functional groups in Paclitexel: (It is not necessary that all functional groups are present in paclitaxel). Tertiary alcohol: Secondary alcohol: Primary alcohol: Ether: Ester: Anhydride: Carboxylic acid: Aldehyde: Ketone: Nitrile: Amine: Amide: Phenol: "Phenyl" groups:
Classes Of Functional Groups
Organic Chemistry deals mostly with carbon and hydrogens, also called hydrocarbons, but those groups which replace hydrogen and bonds with carbon to give a characteristic nature, unique of their own, to the hydrocarbon they are attached to, are called functional groups. All the compounds belonging to a functional group undergo reactions in a similar pattern and are known to have similar physical and chemical properties.
Characteristics Of Functional Groups
In organic chemistry, we encounter a number of special substituent groups which are attached to the hydrocarbon backbone. These groups impart certain characteristics to the molecule of which it is a part of and thus, become the highlight of that particular molecule.
IUPAC Nomenclature
In Chemistry, IUPAC stands for International Union of Pure and Applied Chemistry which suggested a systematic naming approach for the organic and inorganic compounds, as in the beginning stage of nomenclature one single chemical compound was named in many ways by which lead to confusion. The need for this approach aroused as the number of chemical compounds newly discovered were increasing (approximately 32 million compounds) and the basic concept of nomenclature i.e. the trivial nomenclature and the derived system of nomenclature failed to overcome the challenge. It is an important task to name a chemical compound systematically and unambiguously which reduces lots of confusion about the newly reported compounds.
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