Problem 2.29 NH₂ amphetamine Compounds like amphetamine that contain nitrogen atoms are protonated by the HCI in the gastric juices of the stomach, and the resulting salt is then deprotonated in the basic environment of the intestines to regenerate the neutral form. Write proton transfer reactions for both of these processes. In which form will amphetamine pass through a cell membrane?
Problem 2.29 NH₂ amphetamine Compounds like amphetamine that contain nitrogen atoms are protonated by the HCI in the gastric juices of the stomach, and the resulting salt is then deprotonated in the basic environment of the intestines to regenerate the neutral form. Write proton transfer reactions for both of these processes. In which form will amphetamine pass through a cell membrane?
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter23: Amines
Section: Chapter Questions
Problem 23.31P
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Transcribed Image Text:Problem 2.29
2 °
NH₂
amphetamine
Compounds like amphetamine that contain nitrogen atoms are protonated by
the HCI in the gastric juices of the stomach, and the resulting salt is then
deprotonated in the basic environment of the intestines to regenerate the
neutral form. Write proton transfer reactions for both of these processes. In
which form will amphetamine pass through a cell membrane?
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