Problem 2.29 NH₂ amphetamine Compounds like amphetamine that contain nitrogen atoms are protonated by the HCI in the gastric juices of the stomach, and the resulting salt is then deprotonated in the basic environment of the intestines to regenerate the neutral form. Write proton transfer reactions for both of these processes. In which form will amphetamine pass through a cell membrane?

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter19: Carboxylic Anhydrides, Esters, And Amides
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Problem 2.29
2 °
NH₂
amphetamine
Compounds like amphetamine that contain nitrogen atoms are protonated by
the HCI in the gastric juices of the stomach, and the resulting salt is then
deprotonated in the basic environment of the intestines to regenerate the
neutral form. Write proton transfer reactions for both of these processes. In
which form will amphetamine pass through a cell membrane?
Transcribed Image Text:Problem 2.29 2 ° NH₂ amphetamine Compounds like amphetamine that contain nitrogen atoms are protonated by the HCI in the gastric juices of the stomach, and the resulting salt is then deprotonated in the basic environment of the intestines to regenerate the neutral form. Write proton transfer reactions for both of these processes. In which form will amphetamine pass through a cell membrane?
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