Predict the major product(s) of the following reactions. Justify your reasoning for the product you chose in a sentence. You may assume each step is followed by an aqueous workup that neutralizes any leftover reagents and/or charge on the compound.
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
Predict the major product(s) of the following reactions. Justify your reasoning for the product you chose in a sentence. You may assume each step is followed by an aqueous workup that neutralizes any leftover reagents and/or charge on the compound.
![The image shows two chemical reactions involving organic compounds. Each reaction is depicted with starting materials, reagents, and conditions.
1. **Reaction One:**
- **Starting Material:** An organic compound with an ester functional group and a conjugated double bond.
- **Reagent:** Sodium azide (NaN₃).
- **Condition:** The reaction is carried out at 100°C.
- There is an arrow indicating that the reaction leads to a new product, although the specific product is not shown in this image.
2. **Reaction Two:**
- **Starting Material:** An organic compound with a brominated ketone.
- **Reagent:** Sodium ethoxide (NaOEt).
- **Condition:** The reaction is conducted in ethanol (EtOH) at 4°C.
- An arrow indicates the progression to the product, which is not explicitly shown in the image.
These reactions are typical in organic synthesis, involving nucleophilic substitutions or other transformations under specified conditions.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fce8827c4-1422-4db4-bd87-5e9d779d6c3b%2F1eeb6bcc-424a-480c-b5af-9a089058e366%2Funcvdoh_processed.jpeg&w=3840&q=75)
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