Predict the expected major products of the following reaction sequer I ОН 1. t-BuOK 2. KMnO4, NaOH, cold _OH + CO2 ОН ОН + enantiomer ||| OH OH + enantiomer IV +
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
![Predict the expected major products of the following reaction sequence.
1
OH
OI
Oll
O III
SO IV
OV
1. t-BuOK
2. KMnO4, NaOH, cold
+ CO₂
11
OH
OH
OH
+ enantiomer
|||
Qo
LOH
OH
+ enantiomer
IV
OH
+ enantiomer
V](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fb7dbf92b-f00b-4c94-8333-49c9a4672aff%2Fb1279d5a-c265-46ec-9590-afb2c94d705c%2Fty88ei_processed.jpeg&w=3840&q=75)
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