PO4- LOH Incorporation of a deoxynucleotide (DNTP) elongates the chain. A 5- 3'OH subsequent nucleotide can 5' be added to the 3'OH. 3' Incorporation of a dideoxynucleotide (ddNTP); 5- 3'OH 3' the ddNTP lacks a 3'OH. 5' Chain elongation is terminated. No additional nucleotides can be added PO4. HO- 5- 3' 5' due to the lack of a 3'OH. FIGURE 9.11 Chain Termination by a Dideoxynucleotide Once a dideoxynucleotide is incorporated into a growing strand, additional nucleotides cannot be added.
PO4- LOH Incorporation of a deoxynucleotide (DNTP) elongates the chain. A 5- 3'OH subsequent nucleotide can 5' be added to the 3'OH. 3' Incorporation of a dideoxynucleotide (ddNTP); 5- 3'OH 3' the ddNTP lacks a 3'OH. 5' Chain elongation is terminated. No additional nucleotides can be added PO4. HO- 5- 3' 5' due to the lack of a 3'OH. FIGURE 9.11 Chain Termination by a Dideoxynucleotide Once a dideoxynucleotide is incorporated into a growing strand, additional nucleotides cannot be added.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
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How is a dideoxynucleotide different from a deoxynucleotide?
Transcribed Image Text:PO4-
LOH Incorporation of a
deoxynucleotide (DNTP)
elongates the chain. A
5-
3'OH
subsequent nucleotide can
5'
be added to the 3'OH.
3'
Incorporation of a
dideoxynucleotide (ddNTP);
5-
3'OH
3'
the ddNTP lacks a 3'OH.
5'
Chain elongation is
terminated. No additional
nucleotides can be added
PO4.
HO-
5-
3'
5' due to the lack of a 3'OH.
FIGURE 9.11 Chain Termination by a Dideoxynucleotide Once
a dideoxynucleotide is incorporated into a growing strand, additional
nucleotides cannot be added.
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