Please solve for Kd given these values. thank you. Ligand- Receptor Complex Ligand (mM) (mM) 0 0 0.067 0.994 0.125 1.37 0.25 2.04 1 2.98 2 3.09

From the Hill Plot below, the of the first binding event for the receptor-ligand system under study is: Q1 4 nM 10 μΜ -2 nM 2 nM Calculate the Hill Coefficient from the receptor-ligand binding data below: Q2 4 100 2 3 (077) log 10 8 6 4 2 0 -2 -4 -6 -6 -4 -2 0 2 4 log [L] (nM) 6 8 10

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Explain in detail the funcations and signalling and activation of ephrin receptor EPHB2. Give step by step explanation

Describe three ways that the body is able to utilize a single ligand in multipleways by multiple cells? Give examples of each.

2022) . Join: 739526. P 7 R 888 F4 Chemical messengers that cross the synapse bind to _ channels, which create. Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. b a Ligand gated; Action с ce7-4f96-ba96-ba1e2373d5e9 Wk7: Q5 Homework Unanswered Due Today, 11:59 PM d Voltage gated; Graded Ligand gated; Graded Voltage gated; Action Unanswered. 2 attempts left % 5 OCT 19 F5 T ^ 6 ♫ dity STA e MacBook Air F6 Y & 7 F7 C * 00 8 DII FB ( 9 potentials. DD F9 O ) O F10 P F11 No C Subm + =

explain in detail ephrin receptor EPHB2  receptor interaction with PDZ ligand. give full step by step explanantion.

Buprenorphine is a partial agonist at mu opioid receptors and is used for opioid maintenance treatment (OMT) in patients with opioid use disorder (OUD). Buprenorphine is formulated in a product that contains the mu opioid receptor antagonist, naloxone. What is the purpose of naloxone in this formulation? O To increase the magnitude of response to the partial agonist. O To reduce the likelihood that buprenorphine will be injected intravenously. O To delay the response to buprenorphine. O To provide pain relief to the patient who has OUD.

Using the cultured cells used in this experiment and described in the introduction, how would you approach determining the potency of an agonist to the D2 receptor?

Please refer to the model, the answer may be brief.. thank you so much for answering both... i appreciate it1. Explain the mechanism of action of the adenyl cyclic system using a schematic diagram. 2. Cite a metabolic pathway where active protein kinase is needed and explain its mechanism of action