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Please answer parts a and b

Please answer parts a and b

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Please answer parts a and b
Extracollular fluid The" "Sodium-Potassium Pump" is also referred to as the "Na*/K* pump" or the "Na*/K* ATPase protein". This pump protein cannot function without a molecule of ATP. This protein plays a role in transport of two ions: Three Na* ions are pumped out of the cell and two K* are pumped into the cell. Both ions are moved against their concentration gradients. Concentration gradients are maintained by the Na+/K+ ATPase via active transport. Intracellular fluid Na 15 mM Na 145 mM K* 150 mM K+ 4 mM ATP 3Na 2K ADR The Sodium- Glucose Linked Transporter 1 (SGLT-1) protein is a sodium-glucose cotransporter found in the cells that line the small intestine. SGLT-1 does not use ATP for transport, but energy for uphill glucose transport is provided by the sodium gradient maintained by the Na*/K* ATPase protein.
Transcribed Image Text:Extracollular fluid The" "Sodium-Potassium Pump" is also referred to as the "Na*/K* pump" or the "Na*/K* ATPase protein". This pump protein cannot function without a molecule of ATP. This protein plays a role in transport of two ions: Three Na* ions are pumped out of the cell and two K* are pumped into the cell. Both ions are moved against their concentration gradients. Concentration gradients are maintained by the Na+/K+ ATPase via active transport. Intracellular fluid Na 15 mM Na 145 mM K* 150 mM K+ 4 mM ATP 3Na 2K ADR The Sodium- Glucose Linked Transporter 1 (SGLT-1) protein is a sodium-glucose cotransporter found in the cells that line the small intestine. SGLT-1 does not use ATP for transport, but energy for uphill glucose transport is provided by the sodium gradient maintained by the Na*/K* ATPase protein.
Researchers studying the SGLT1 protein were able to make artificial cells that contained the SGLT-1 protein and a lipid bi-layer. The graph below shows the relationship between glucose transport and Na+ concentration of the solution that these artificial cells were placed in. Na* Na+ Na glucose Using the information from the figure to the right and the graph below, explain briefly how the SGLT-1 protein functions to transport both Nat and glucose? Use your understanding of protein structure & function, to describe this co-transport. a. A В The graph shows the relationship between glucose transport and Na* concentration of the solution that these artificial cells were placed in. 30 b. What would happen to glucose transport via the SGLT1 protein in the presence of an ATPase inhibitor? Describe briefly. HINT: Check description of transport in page 2 10 (ATPase is an enzyme that breaks down ATP into ADP and free phosphate ion, providing energy, an inhibitor prevents its action). 20 40 60 80 100 120 [Na'] (mM) D-H] Glucose Uptake pmol / mg protein x min
Transcribed Image Text:Researchers studying the SGLT1 protein were able to make artificial cells that contained the SGLT-1 protein and a lipid bi-layer. The graph below shows the relationship between glucose transport and Na+ concentration of the solution that these artificial cells were placed in. Na* Na+ Na glucose Using the information from the figure to the right and the graph below, explain briefly how the SGLT-1 protein functions to transport both Nat and glucose? Use your understanding of protein structure & function, to describe this co-transport. a. A В The graph shows the relationship between glucose transport and Na* concentration of the solution that these artificial cells were placed in. 30 b. What would happen to glucose transport via the SGLT1 protein in the presence of an ATPase inhibitor? Describe briefly. HINT: Check description of transport in page 2 10 (ATPase is an enzyme that breaks down ATP into ADP and free phosphate ion, providing energy, an inhibitor prevents its action). 20 40 60 80 100 120 [Na'] (mM) D-H] Glucose Uptake pmol / mg protein x min
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