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Phosphatidic acid phosphatase (PAP), also called lipin, converts phosphatidate to diacylglycerol (DAG). Diacylglycerol kinase converts DAG to phosphatidate.

Phosphatidic acid phosphatase (PAP), also called lipin, converts phosphatidate to diacylglycerol (DAG). Diacylglycerol kinase converts DAG to phosphatidate.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Phosphatidic acid phosphatase (PAP), also called lipin, converts phosphatidate to diacylglycerol (DAG). Diacylglycerol kinase converts DAG to phosphatidate. CH2-O- CH CH₂ phosphatidic acid phosphatase H₂O P₁ ADP ATP diacylglycerol kinase Concentration will increase CH2-O- TE R₂ CH CH₂-OH -R₁ Consider the effect of a mutation in the PAP gene on triacylglycerol and phospholipid synthesis. Classify each lipid based on whether its concentration will increase or decrease if the gene for PAP is underexpressed. Concentration will decrease
Transcribed Image Text:Phosphatidic acid phosphatase (PAP), also called lipin, converts phosphatidate to diacylglycerol (DAG). Diacylglycerol kinase converts DAG to phosphatidate. CH2-O- CH CH₂ phosphatidic acid phosphatase H₂O P₁ ADP ATP diacylglycerol kinase Concentration will increase CH2-O- TE R₂ CH CH₂-OH -R₁ Consider the effect of a mutation in the PAP gene on triacylglycerol and phospholipid synthesis. Classify each lipid based on whether its concentration will increase or decrease if the gene for PAP is underexpressed. Concentration will decrease
phospholipids generated from CDP-DAG and a polar head group phospholipids generated from DAG and activated head groups R2–CO—CH CH, O R₂-C-O-CH Answer Bank || CH₂0-C-R₁ ofo CH₂-O-F -O-8-R₁ 0 CH₂-O-P-O-CH₂-CH-COO™ + 0 NH3 I triacylglycerols O CH₂-O-C-R₁ R2-8-0-CH CH2O o=d-0 O H OH OH H OH HO H H H OH
Transcribed Image Text:phospholipids generated from CDP-DAG and a polar head group phospholipids generated from DAG and activated head groups R2–CO—CH CH, O R₂-C-O-CH Answer Bank || CH₂0-C-R₁ ofo CH₂-O-F -O-8-R₁ 0 CH₂-O-P-O-CH₂-CH-COO™ + 0 NH3 I triacylglycerols O CH₂-O-C-R₁ R2-8-0-CH CH2O o=d-0 O H OH OH H OH HO H H H OH
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