Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
Persons with high serum cholesterol are at risk of cardiovascular disease. Physicians treat such persons with inhibitors of the enzyme HMG-COA reductase, the enzyme that controls cholesterol synthesis. You are a biochemist at a drug company and have just discovered a chemical that binds irreversibly to HMG-CoA reductase and inhibits its activity. You describe your discovery to the FDA and they immediately reject the compound for human use. Why do you think they came up with this decision?. * The inhibitor will only temporarily inhibit the HMG-COA reductase and thus deemed inefficient. O The inhibitor will permanently inhibit the HMG-COA reductase and thus deemed toxic. The inhibitor will cause cardiovascular diseases. The inhibitor has no significant effect on HMG-COA reductase due to metabolic redundancy.

Persons with high serum cholesterol are at risk of cardiovascular disease. Physicians treat such persons with inhibitors of the enzyme HMG-COA reductase, the enzyme that controls cholesterol synthesis. You are a biochemist at a drug company and have just discovered a chemical that binds irreversibly to HMG-CoA reductase and inhibits its activity. You describe your discovery to the FDA and they immediately reject the compound for human use. Why do you think they came up with this decision?. * The inhibitor will only temporarily inhibit the HMG-COA reductase and thus deemed inefficient. O The inhibitor will permanently inhibit the HMG-COA reductase and thus deemed toxic. The inhibitor will cause cardiovascular diseases. The inhibitor has no significant effect on HMG-COA reductase due to metabolic redundancy.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
See similar textbooks
icon
Related questions
Question
Mcq
Persons with high serum cholesterol are at risk of cardiovascular disease. Physicians treat such persons with inhibitors of the enzyme HMG-COA reductase, the enzyme that controls cholesterol synthesis. You are a biochemist at a drug company and have just discovered a chemical that binds irreversibly to HMG-CoA reductase and inhibits its activity. You describe your discovery to the FDA and they immediately reject the compound for human use. Why do you think they came up with this decision?. * The inhibitor will only temporarily inhibit the HMG-COA reductase and thus deemed inefficient. O The inhibitor will permanently inhibit the HMG-COA reductase and thus deemed toxic. The inhibitor will cause cardiovascular diseases. The inhibitor has no significant effect on HMG-COA reductase due to metabolic redundancy.
Transcribed Image Text:Persons with high serum cholesterol are at risk of cardiovascular disease. Physicians treat such persons with inhibitors of the enzyme HMG-COA reductase, the enzyme that controls cholesterol synthesis. You are a biochemist at a drug company and have just discovered a chemical that binds irreversibly to HMG-CoA reductase and inhibits its activity. You describe your discovery to the FDA and they immediately reject the compound for human use. Why do you think they came up with this decision?. * The inhibitor will only temporarily inhibit the HMG-COA reductase and thus deemed inefficient. O The inhibitor will permanently inhibit the HMG-COA reductase and thus deemed toxic. The inhibitor will cause cardiovascular diseases. The inhibitor has no significant effect on HMG-COA reductase due to metabolic redundancy.
Expert Solution
steps

Step by step

Solved in 3 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Reproductive system
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON
SEE MORE TEXTBOOKS