People with recessive disorders are usually born to normal parents who are both heterozygotes which means that both parents are carriers of the dominant allele for the disorder but appear normal themselves. Select one: True False
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People with recessive disorders are usually born to normal parents who are both heterozygotes which means that both parents are carriers of the dominant allele for the disorder but appear normal themselves.
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- Hemophilia is a sex-linked trait. A person with hemophilia is lacking certain proteins that are necessary for normal blood clotting. Hemophilia is caused by a recessive allele so use "N" for normal and "n" for hemophilia. Since hemophilia is sex-linked, remember a woman will have two alleles (NN or Nn or nn) but a man will have only one allele (N or n). A woman who is heterozygous (a carrier) for hemophilia marries a normal man: a.What are the genotypes of the parents? b.What is the probability that a male offspring will have hemophilia? c. What is the probability of having a hemophiliac female offspring?Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Mary is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Paul whose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibits sickle cell anemia. What are the genotypes of Jane and Paul? If they plan to have four children, what is the probability that: all their children will be normal? _________________________________ they will have a son with Huntington’s disease? _________________________ they will have a daughter inflicted with both conditions?________________Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Jane is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Paul whose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibits sickle cell anemia. What are the genotypes of Jane and Paul?
- Hemophilia is a sex-linked recessive trait. A male hemophiliac and phenotypically normal female have a son with hemophilia. They would like to have one more child. What is the probability of having a child without hemophilia? Explain using a Punnett square. Is it possible for a girl to be born with hemophilia? Explain.Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Jane is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Paul whose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibit sickle cell anemia. What are the genotypes of Jane and Paul? If they plan to have four children, what is the probability that: all their children will be normal? _________________________________ they will have a son with Huntington’s disease? _________________________ they will have a daughter inflicted with both conditions?________________Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Jane is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Paul whose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibit sickle cell anemia. What are the genotypes of Jane and Paul? Jane:______________________________Paul:_____________________________ If they plan to have four children, what is the probability that: all their children will be normal? _________________________________ they will have a son with Huntington’s disease? _________________________ they will have a daughter inflicted with both conditions?________________
- Albinism is an autosomal (not sex-linked) recessive trait. A man and woman are both of normal pigmentation and have one child out of three who is albino (without melanin pigmentation). What are the genotypes of the albino's parents? One parent must be homozygous for the recessive allele; the other parent can be homozygous dominant, homozygous recessive, or heterozygous. Both parents must be homozygous dominant. One parent must be heterozygous; the other parent can be homozygous dominant, homozygous recessive, or heterozygous. Both parents must be heterozygous. One parent must be homozygous dominant; the other parent must be heterozygous. O000Considering a common autosomal recessive trait: (Read each statement carefully. Select all of the statements below that are true (that you agree with). Leave any statements that are false (that you do not agree with) un- selected.) the unaffected biological siblings of an affected person should be heterozygotes. an unaffected woman and an affected man have at most a 100% probability of having a affected child. an affected person should have an affected parent. The unaffected offspring of an affected parent must be carriers.People with polydactyly have more than five fingers or toes on their hands or feet. Polydactyly results from an autosomal dominant genetic disorder. Draw a pedigree for a family with polydactyly, using the following information: Zack has polydactyly but his wife, Zoe does not. Zack and Zoe’s daughter Yolanda has polydactyly but their son Yogi does not. Yolanda has two children with her husband, Xavier, who does not have polydactyly: Wilma, who is normal and Wade, who has polydactyly. Use your pedigree to determine what is Zoe's genotype. A) DD B)dd C)Dd
- Huntington's disease is an inherited autosomal dominant disorder that can affect both men and women. Imagine a couple has had seven children, and later in life, the husband develops Huntington's disease. He is tested and it is discovered he is heterozygous for the disease allele, Hh. The wife is also genetically tested for the Huntington's disease allele, and her test results show she is unaffected, hh. What is the percent probability that the first child of this couple will have Huntington's disease? probability: % What is the percent probability that two of the seven children will have Huntington's disease? probability: %Albinism (lack of skin pigmentation) is caused by an autosomal recessive allele. A man and woman, both normally pigmented, have an albino child together. For this trait, what is the genotype of both parents? Options Below: homozygous recessive homozygous dominant heterozygous hemizygous unknown, because not enough information is providedIn humans, cystic fibrosis and albinism are both inherited as independently assorting autosomal recessive traits. Use f to represent the recessive allele for cystic fibrosis and F for the allele for the unaffected condition. Use A to represent the dominant allele for normal melanin and a for the recessive allele for albinism. A man is albino and heterozygous for cystic fibrosis. His wife has the unaffected phenotype for both traits, although her father had cystic fibrosis and her mother is albino. 4a. What is the genotype of the wife 4b.What is the probability that a child of this couple is albino and has cystic fibrosis? 4c.What is the probability that a child of this couple is a girl who is albino and has cystic fibrosis? 4d.What is the probability that a child of this couple is normal for both traits?