Part C If, in addition to the constraints on glucose concentration listed previously, we have in the liver cell ATP concentration 5 mM and ADP concentration = 4 mM, what is the theoretical concentration of glucose-6-phosphate at equilibrium at pH = 7.4 and 37 °C? Express your answer to three significant figures and include the appropriate units. Theoretical concentration = Submit Request Answer μA Value Units ?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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3-2.8

Part C
If, in addition to the constraints on glucose concentration listed previously, we have in the liver cell ATP concentration =
what is the theoretical concentration of glucose-6-phosphate at equilibrium at pH = 7.4 and 37 °C?
Express your answer to three significant figures and include the appropriate units.
Theoretical concentration = Value
Submit
μÅ
Request Answer
Units
?
5 mM and ADP concentration = 4 mM,
Transcribed Image Text:Part C If, in addition to the constraints on glucose concentration listed previously, we have in the liver cell ATP concentration = what is the theoretical concentration of glucose-6-phosphate at equilibrium at pH = 7.4 and 37 °C? Express your answer to three significant figures and include the appropriate units. Theoretical concentration = Value Submit μÅ Request Answer Units ? 5 mM and ADP concentration = 4 mM,
The first reaction in glycolysis is the phosphorylation of glucose:
This is a thermodynamically unfavorable process, with AGO!
Part A
Equilibrium concentration = Value
Submit
Part B
In a liver cell at 37 °C the concentrations of both phosphate and glucose are normally maintained at about 5 mM each. What would be the equilibrium concentration
of glucose-6-phosphate, according to the above data?
Express your answer to two significant figures and include the appropriate units.
Request Answer
AGO! =
Submit
μÅ
μĂ
Pi + glucose
Value
Request Answer
=
This very low concentration of the desired product would be unfavorable for glycolysis. In fact, the reaction is coupled to ATP hydrolysis to give the overall reaction
ATP + glucose glucose-6-phosphate + ADP + H+
What is AGO for the coupled reaction?
Express your answer to three significant figures and include the appropriate units.
Units
→glucose-6-phosphate + H₂O
+13.8 kJ/mol.
Units
?
?
Transcribed Image Text:The first reaction in glycolysis is the phosphorylation of glucose: This is a thermodynamically unfavorable process, with AGO! Part A Equilibrium concentration = Value Submit Part B In a liver cell at 37 °C the concentrations of both phosphate and glucose are normally maintained at about 5 mM each. What would be the equilibrium concentration of glucose-6-phosphate, according to the above data? Express your answer to two significant figures and include the appropriate units. Request Answer AGO! = Submit μÅ μĂ Pi + glucose Value Request Answer = This very low concentration of the desired product would be unfavorable for glycolysis. In fact, the reaction is coupled to ATP hydrolysis to give the overall reaction ATP + glucose glucose-6-phosphate + ADP + H+ What is AGO for the coupled reaction? Express your answer to three significant figures and include the appropriate units. Units →glucose-6-phosphate + H₂O +13.8 kJ/mol. Units ? ?
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