Parental strand -MutH -Newly made strand Mutl -Muts Incorrect MutH makes a cut in the nonmethylated strand. MutU (not shown) separates the DNA strands at the cleavage site, and an exonuclease (not shown) digests the nonmethylated strand until It passes the site where MutS is bound, removing the Incorrect base. base MutH cleavage site DNA polymerase fills in the vacant reglon. DNA ligase seals the end. The mismatch has been repalred correctly. А Н FIGURE 19.20 Mimatch repair in E. coli. In this example, the methylated adenine is designated with an m.

Q: What kind of changes Transcription Requires in Chromatin Structure and Nucleosome Position?

A: Transcription is the process of the formation of an RNA strand complementary to the DNA strand that…

Q: In the image below, which arrow denotes the protein that forms the nested DNA loops in chromatin?…

A: Linker histones (H1 and its variations) or HMG proteins bind lengths of DNA that connect adjacent…

Q: Why is only one strand transcribed, and is the same strand of DNAalways transcribed?

A: DNA (Deoxyribo Nucleic Acid) is the genetic material in all the prokaryotes are eukaryotes. DNA is…

Q: what is the highly compacted strongly staining region of the chromosome with no transcriptional…

A: The highly compacted strongly region of the chromosome with no transcriptional activity is…

Q: If circular B-DNA is positively supercoiled, will these supercoils be left- or right-handed?

A: Supercoiling of DNA is a biological process that regulated the unwinding and rewinding of the DNA…

Q: What is the difference between leading strand and lagging strand synthesis?

A: DNA is a genetic material which appear as two stranded ladder like structure . It basically…

Q: Euchromatin is said to be transcriptionally-active while Heterochromatin is said to be…

A: Euchromatin exists in decondensed form and is found in the distal arms of the chromosome. It is…

Q: why the repressor proteins bind with the major groove in the DNA helix?

A: DNA is a double helical structure as described by Watson and crick consisting of two loops that is…

Q: Why do we say replication and transcription is highly stochastic? There are just 4 types of…

A: The process of DNA replication or transcription, we have noticed that there are many steps involved,…

Q: What are transposable or mobile DNA elements?

A: According to the question, we have to give the information on transposable or mobile DNA elements.…

Q: What makes the deletion of a gene?

A: Deletion is a type of mutation in which a part or sequence of a chromosome that can be a single base…

Q: Where is the DNA that encodes the last 13 residues of the variable domain?

A: Antibodies are made up of four polypeptide chains namely two heavy chains and two light chains (L).…

Q: How does discontinuous synthesis of the lagging strand keep up with continuous synthesis of the…

A: The DNA is always synthesized in the 5′ → 3′ directly with nucleoside triphosphates (NTPs) acting as…

Q: onsider the following segment of DNA, which is part of a linear chromosome: LEFT…

A: Answer.  Transcription is a process of the formation of transcript (RNA). It takes place by the…

Q: IS the order of the base pairs exactly the same in the 2 new DNA strands?

A:

Q: What is histone ocatmer?

A: The histones are highly basic proteins present in eukaryotic cells nuclei. It packs and order the…

Q: How do these engineered nucleases effect a change in the genomic DNA sequence?

A: Genome editing is a technique used to precisely and efficiently modify DNA within a cell. It…

Q: In mismatch repair, how does the cell "know" which strand is the correct strand and which strand is…

A: During DNA synthesis,  DNA polymerases keep checking their work and keep fixing the majority of…

Q: Consider the following segment of DNA, which is part of a linear chromosome: LEFT…

A: DNA replication is the process by which the DNA is copied in the cell to make up more number of DNA…

Q: What is the purpose of heterochromatin and does heterochromatin transcribed?

A: Heterochromatin is a condensed or tightly packed form of DNA that comes in multiple varieties. These…

Q: What is the difference between the template strand and the nontemplate strand?

A: Deoxyribonucleic acid (DNA) is the hereditary unit of life, which carries the genetic information in…

Q: What is the cause of discontinous synthesis of DNA on one of the parental strand of DNA?

A: DNA or deoxyribonucleic acid is a polymer of deoxyribonucleotides connected together via…

Q: Why are transposable elements often called genomic parasites?

A: Transposable elements, also known as jumping genes are short segments of DNA, which have special…

Q: What is the major difference between a linkage map and a physical map of a chromosome?

A: The chromosomes are the microscopic threadlike structure of the cell that carries the hereditary…

Q: What are the different terms used to describe the two strands of DNA involved in transcription?

A: Transcription is a process of formation of RNA. It is DNA dependent RNA synthesis process. Process…

Q: Which of the DNA strands is used in transcription?

A: Step 1 Transcription is the formation of RNA (ribonucleic acid) over the template DNA. It generates…

Q: What happens when a nonsense mutation is introduced into a transposon's gene encoding transposase?

A: A non-sense mutation is a mutation that terminates translation earlier resulting in the formation of…

Q: Why is the genome contained within a membrane?

A: A genome is a complete set of "genetic information" in an organism. It stores all of the information…

Q: What features distinguish a transposon from a retrotransposon?How are their sequences different, and…

A: The transposons and retrotransposons are the deoxyribonucleic acid (DNA) sequences that transfer…

Q: What is the difference in the requirement for a primer in RNA transcription compared to DNA…

A: DNA replication is the biological process of producing two identical replicas of DNA from one…

Q: How is the template strand the one being transcribed but the coding strand is the one that has the…

A: Introduction Because it serves as a template for transcription, the DNA strand from which mRNA is…

Q: Which part of the central dogma is achieved by the process of translation?

A: The central dogma of molecular biology is a foundational system that depicts the flow of hereditary…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.