Orciprenaline(C11H17N03, 211.258 g/mol) is a bronchodilator used in the treatment of asthma. The BP assay for orciprenaline tablets is described below. Read the following information carefully and answer the questions below. (Record your answers in decimal notation to the indicated significant figures OR decimal places) ASSAY - 20 tablets weighing 2.597 g were crushed to a powder. A portion of the crushed powder (0.5456 g) was shaken with 50 mL of 0.1 M HI, the mixture was filtered and made up to 100 mL. 10 mL of this solution was further diluted to 100 mL with 0.1 M HCI. The measured absorbance of the diluted solution at 276 nm was 0.582. Additional information: A1% 72.3, stated content = 20 mg Calculate: a) The concentration of orciprenaline in the diluted solution in mg/L b) The actual amount of orciprenaline (in mg) in the powder assayed. c) The actual amount of orciprenaline (in mg) per tablet. d) The percentage of stated content of per tablet.
Orciprenaline(C11H17N03,
211.258 g/mol) is a bronchodilator
used in the treatment of asthma.
The BP assay for orciprenaline
tablets is described below. Read the
following information carefully and
answer the questions below.
(Record your answers in decimal
notation to the indicated significant
figures OR decimal places)
ASSAY - 20 tablets weighing 2.597 g
were crushed to a powder. A
portion of the crushed powder
(0.5456 g) was shaken with 50 mL of
0.1 M HI, the mixture was filtered
and made up to 100 mL. 10 mL of
this solution was further diluted to
100 mL with 0.1 M HCI. The
measured absorbance of the
diluted solution at 276 nm was
0.582. Additional information: A1%
72.3, stated content = 20 mg
Calculate:
a) The concentration of
orciprenaline in the diluted solution
in mg/L
b) The actual amount of
orciprenaline (in mg) in the powder
assayed.
c) The actual amount of
orciprenaline (in mg) per tablet.
d) The percentage of stated content
of per tablet.
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