Opening of voltage-gated channels is driven by an intramembrane electric field acting on charged voltage-sensor domains. These domains move across the membrane and generate gating (displacement) currents. When these currents are integrated over time, they produce the gating charge generated by a population of channels. What would be the gating charge passing through the external circuit when the flat array of charges moves across the distance a inside the membrane? The hydrophobic thickness of the membrane is d, the dielectric constant ɛ, the density of charges is O and the area of the membrane is A (provide an analytic solution).

icon
Related questions
Question
Opening of voltage-gated channels is driven by an intramembrane electric field acting on charged
voltage-sensor domains. These domains move across the membrane and generate gating
(displacement) currents. When these currents are integrated over time, they produce the gating
charge generated by a population of channels. What would be the gating charge passing through the
external circuit when the flat array of charges moves across the distance a inside the membrane?
The hydrophobic thickness of the membrane is d, the dielectric constant ɛ, the density of charges is
O and the area of the membrane is A (provide an analytic solution).
start
end
A
A
a
d
d
Transcribed Image Text:Opening of voltage-gated channels is driven by an intramembrane electric field acting on charged voltage-sensor domains. These domains move across the membrane and generate gating (displacement) currents. When these currents are integrated over time, they produce the gating charge generated by a population of channels. What would be the gating charge passing through the external circuit when the flat array of charges moves across the distance a inside the membrane? The hydrophobic thickness of the membrane is d, the dielectric constant ɛ, the density of charges is O and the area of the membrane is A (provide an analytic solution). start end A A a d d
Expert Solution
steps

Step by step

Solved in 2 steps

Blurred answer