On October 29, the North Carolina Division of Public Health (NCDPH) received a report of three cases of hemolytic uremic syndrome (HUS) among children caused by Escherichia coli O157:H7 infection. All three children visited a petting zoo at the North Carolina State Fair during October 15-24. Case finding efforts by NCDPH identified 105 other persons who had become ill with diarrhea after attending the fair. A case-control study was undertaken to identify risk factors for infection with E. coli 0157:H7. Forty-five case-patients and 188 controls who attended the fair and did not get sick were enrolled in the study. A p-value of 0.05 was set as the cutoff for statistical significance. Thirty-six (80%) of 45 case-patients visited the petting zoo, compared with 64 (36%) of 187 controls (odds ratio= 7.7; p<0.0001). In an analysis of case-patients and controls who were aged <6 years who visited the petting zoo, the following results were found: Exposure Touching or stepping in manure Falling or sitting on the ground Use of a pacifier or spill-proof cup or sucking on one's thumb while at the zoo Use of alcohol-based hand sanitizer Awareness of risk of disease from contact with livestock* *among parents who accompanied the children Use of alcohol-based hand sanitizer Odds ratio 6.9 3.2 11.0 1.9 0.1 None of the above Among children who visited the petting zoo, which exposures might be protective factors for infection with E. coli O157:H7? Awareness of risk of disease from contact with livestock (among parents) Use of a pacifier or spill-proof cup or sucking on one's thumb while at the zoo p-value 0.001 0.02 0.001 0.6 0.02
On October 29, the North Carolina Division of Public Health (NCDPH) received a report of three cases of hemolytic uremic syndrome (HUS) among children caused by Escherichia coli O157:H7 infection. All three children visited a petting zoo at the North Carolina State Fair during October 15-24. Case finding efforts by NCDPH identified 105 other persons who had become ill with diarrhea after attending the fair. A case-control study was undertaken to identify risk factors for infection with E. coli 0157:H7. Forty-five case-patients and 188 controls who attended the fair and did not get sick were enrolled in the study. A p-value of 0.05 was set as the cutoff for statistical significance. Thirty-six (80%) of 45 case-patients visited the petting zoo, compared with 64 (36%) of 187 controls (odds ratio= 7.7; p<0.0001). In an analysis of case-patients and controls who were aged <6 years who visited the petting zoo, the following results were found: Exposure Touching or stepping in manure Falling or sitting on the ground Use of a pacifier or spill-proof cup or sucking on one's thumb while at the zoo Use of alcohol-based hand sanitizer Awareness of risk of disease from contact with livestock* *among parents who accompanied the children Use of alcohol-based hand sanitizer Odds ratio 6.9 3.2 11.0 1.9 0.1 None of the above Among children who visited the petting zoo, which exposures might be protective factors for infection with E. coli O157:H7? Awareness of risk of disease from contact with livestock (among parents) Use of a pacifier or spill-proof cup or sucking on one's thumb while at the zoo p-value 0.001 0.02 0.001 0.6 0.02
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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